The list of news
| 2025/04/01 | As a new key technology development program, Mouse Phenomics Division was established in April 2025 by reorganizing the Mouse Phenotype Analysis Division. |
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| 2023/12/26 | A review paper on next-generation electron microscopy techniques has been published in the Journal of Molecular Cell Biology. The paper, in which Dr. Tamura participated, is the result of joint research with RIKEN BDR, RIKEN IMS, Kyoto University and JEOL. Son R. et al., Journal of Molecular Cell Biology 2023. mjad081 |
| 2023/08/31 | A paper demonstrating that heterozygous loss-of-function mutations in the DHX9 gene are associated with neurodevelopmental disorders has been published in the European Journal of Medical Genetics. The paper is the result of collaborative research with Keio University, Niigata University and the National Institute of Genetics. Yamada M.et al., European Journal of Medical Genetics 2023. 66: 104804. |
| 2023/04/01 | As a new key technology development program, the Mouse Phenotype Analysis Division was established in April 2023 by reorganizing the Technology and Development Team for Mouse Phenotype Analysis. |
| 2023/04/01 | Automated hematology analyzer was updated to XN-1000V (sysmex).In clinical biochemical test, LD and ALP measurement methods were replaced by IFCC method for JSCC method. |
| 2023/02/16 | "Interview with women in research positions" has received RIKEN Diversity Award 2022 for the diversity efforts. |
| 2023/01/31 | A review article on ECG from the IMPC project, in which the Mouse Phenotyping Technology Office participates, has been published in Mammalian Genome. Oestereicher MA. et al., Mammalian Genome 2023. 34:180-199. |
| 2023/01/23 | A paper on tertiary lymphoid tissue (TLT) that may be involved in chronic kidney disease (CKD) and end-stage renal disease (ESRD) has been published in Nephrology Dialysis Transplantation. Dr. Tamura participated in the imaging analysis of this paper. Sato Y. et al., Nephrology Dialysis and Transplantation 2023. 38: 26-33. |
| 2022/12/08 | A research paper on high-resolution kidney morphometry using X-ray microscopy has been published in the journal Microscopy. This research is the result of collaboration between RIKEN Engineering Project, Kyoto University, and Rigaku Corporation. Kunishima N., et al., Microscopy 2022. 71:315-323. |
| 2022/10/28 | A research paper on the function of the Exocyst Complex Component 3-like 2 gene during heart formation has been published in Life. This paper is the result of collaborative research with Shiga University of Medical Science, University of Tsukuba, Kobe Gakuin University and Keio University. Watanabe C. et al., Life 2022. 12:1730. |
| 2022/10/21 | A research paper on the function of the Scl39a13/ZIP13 gene in cardiovascular homeostasis has been published in PLOS ONE. This paper is the result of a collaborative research with Tokushima Bunri University, Nagahama Institute of Bio-Science and Technology, RIKEN IMS, Kazusa DNA Research Institute and Maria Hospital in Portugal. Hara T. et al., PLOS ONE 2022. 17: e0276452. |
| 2022/05/20 | Dr. Miura's research paper, "Characterization of single nucleotide polymorphisms for a forward genetics approach using genetic crosses in C57BL/6 and BALB/c substrains of mice" was published in Experimental Animals. https://www.jstage.jst.go.jp/article/expanim/71/2/71_21-0181/_article/-char/en |
| 2022/04/26 | As part of the Diversity initiatives to support women’s active participation, an interview article with Dr. Ikuko Yamada, technical scientist, was published on the BRC website. https://web.brc.riken.jp/en/diversity/interview/220426 |
| 2021/07/29 | Dr. Shibuya and Dr. Tamura published a technical article entitled "New frontiers of X-ray imaging in the life sciences" in the Japanese journal "The Cell" (Vol.53, No.9, 2021). |
| 2021/07/29 | A research paper on "Effects of Pparγ1 deletion on late-stage murine embryogenesis and cells that undergo endocycle." that Dr. Tamura and Dr. Shibuya conducted an imaging analysis as a collaborator has been published in Developmental Biology. This is a joint research with Saitama Medical University, Nippon Medical University and Tokyo Medical University. https://doi.org/10.1016/j.ydbio.2021.07.003 |
| 2021/07/02 |
A paper on "Impact of endogenous melatonin on rhythmic behaviors, reproduction, and survival revealed in melatonin-proficient C57BL/6J congenic mice" that Dr. Furuse and Mr. Miura conducted a behavioral analysis and a genome scan, respectively, as a collaborator has been published in Journal of Pineal Research. It is a joint research with RIKEN Center for Brain Science, State University of New York at Buffalo, Tokyo University and Juntendo University. https://doi.org/10.1111/jpi.12748 https://www.riken.jp/en/news_pubs/research_news/pr/2021/20210624_2/index.html |
| 2021/04/27 |
The phenotyping pipeline 1 was updated. |
| 2021/04/08 |
The International Mouse Phenotyping Consortium, in which our team participates, reports the generation of new mouse mutant strains for more than 5,000 genes, including 2,850 novel null, 2,987 novel conditional-ready and 4,433 novel reporter alleles. These results were published in Nature Genetics. https://doi.org/10.1038/s41588-021-00825-y |
| 2020/12/17 |
A research paper entitled "Targeting oxytocin receptor (Oxtr)-expressing neurons in the lateral septum to restore social novelty in autism spectrum disorder mouse models" that Dr. Furuse and Dr. Tamura conducted a behavioral analysis as a collaborator has been published in Scientific Reports. This is a collaborative research with several universities, including Fukushima Medical University and Tohoku University. https://www.nature.com/articles/s41598-020-79109-0 |
| 2020/08/04 | The RIKEN BRC Website was renewed. With this change, we updated the team website. |
| 2020/06/22 | A paper on "Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity" that Mr. Miura conducted a genome scan analysis as a collaborator has been published in Nature Immunology. This is a joint research with the Osaka University, Kyushu University, and RIKEN IMS. |
| 2020/05/20 | Announcement: On May 20th, RIKEN BRC resumed a part of the bioresource deposition/distribution services. |
| 2020/02/26 |
A research paper on "Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes" that team leader, Dr. Tamura with Dr. Furuse, Dr. Yamada and Dr. Shibuya conducted an imaging and behavioral analysis as a collaborator has been published in Nature Communications. This is a joint research with several research institutes and universities including Osaka University and National Center of Neurology and Psychiatry. https://www.nature.com/articles/s41467-020-14697-z |
| 2019/10/30 | Team leader, Dr. Tamura with Dr. Shibuya and Ms. Tanabe received a letter of appreciation from President of RIKEN, Dr. H. Matsumoto, for the achievement of the "Best Imaging Award" on the 6th International Symposium on Bioimaging / The 28th Annual Meeting of the Bioimaging Society. |
| 2019/10/06 | A paper on "Glial pathology in a novel spontaneous mutant mouse of the Eif2b5 gene: a vanishing white matter disease model" that Technical Scientist, Mr. Miura conducted a gene mapping analysis as a collaborator has been published in Journal of Neurochemistry. This is a joint research with Niigata University, Tokyo University and National Center of Neurology and Psychiatry. |
| 2019/09/23 | Double Winner for Best Imaging Award!! At The 6th International Symposium on Bioimaging / The 28th Annual Meeting of the Bioimaging Society held in Teikyo University Itabashi Campus, Dr. Shibuya has won the Best Image Hamamatsu Award for his presentation "Development of the imaging methods for phenotyping of knockout mice". In addition, Ms. Rumiko Tanabe (Visiting Researcher / Nagahama Institute of Bio-Science and Technology, Nomura Laboratory) has won the Nikon Award for her presentation "Titanium Dioxide Nanoparticle as Perfusion Contrast Agent for Visualization and Diagnosis of Small-Animal Microvessel". https://ja.brc.riken.jp/news/report_20191018_01.html |
| 2019/09/12 |
The interview article "First Person" with Dr. Furuse and Dr. Mizuma (BDR) was published in Disease Models & Mechanisms. https://dmm.biologists.org/content/12/9/dmm042127 |
| 2019/08/09 |
Dr. Furuse's research paper, "A new mouse model of GLUT1 deficiency syndrome exhibits abnormal sleep-wake patterns and alterations of glucose kinetics in the brain" was published in Disease Models & Mechanisms. https://dmm.biologists.org/content/12/9/dmm038828 |
| 2019/08/05 | Dr. Tamura’s newspaper article, "RIKEN Frontline/Mouse Phenotypic Information Analysis, Contributing to Human Health" was published in Nihon Kogyo Shinbun. |
| 2019/07/23 |
Dr. Furuse received a letter of appreciation from President of RIKEN, Dr. H. Matsumoto, for the achievement of the "Kazuo Moriwaki Award". https://ja.brc.riken.jp/news/report_20190723_01.html |
| 2019/07/01 | Team leader, Dr. Tamura with Dr. Kume (BDR), Dr. Kobayashi (ISC) and Dr. Murakawa (IMS) published a Japanese review article entitled "Pathology in the big image data era woven by electron and X-ray imaging technologies". (Pathology and Clinical Medicine No.7, 2019) |
| 2019/07/01 | A new member, Ms. Shundan Jin joined the team as a Technical staff II. |
| 2019/06/27 |
At the 32nd molossinus colloquium held in Hotel Maple Inn Makuhari at Chiba prefecture (organized by Dr. Yuichi Wakabayashi, Chiba Cancer Center), Dr. Furuse has won the Kazuo Moriwaki Award for "The establishing a comprehensive behavioral phenotyping system for mutant and wild-derived mice". https://ja.brc.riken.jp/news/report_20190723_01.html |
| 2018/09/20 |
A paper on "Building a model animal effective for elucidating the pathogenesis of abdominal wall formation and umbilical hernia", that team leader, Dr. Tamura conducted an imaging analysis as a collaborator has been published in Disease Models & Mechanisms. This is a joint research with Jichi Medical University. https://dmm.biologists.org/content/11/10/dmm034611 |
| 2018/09 | This website was revamped. |
| 2018/07/26 |
A paper on "The mechanism that determines the length and thickness of a luminal organ" that team leader, Dr. Tamura conducted an imaging analysis as a collaborator has been published in Nature communications. This is a joint research with RIKEN BDR, and Kobe University. https://www.nature.com/articles/s41467-018-05189-2 |
| 2018/04/01 | A new member, Dr. Hirotoshi Shibuya joined the team as a Post-doctoral Researcher. |
| 2018/04/01 | With the reorganization of the RIKEN BRC, a Technology and Development Team for Mouse Phenotype Analysis was renewed. Dr. Masaru Tamura has arrived as a new team leader. |
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