Overview

  Our Division, Mouse Phenotype Analysis Division, conducted a comprehensive phenotype analysis project for knockout mice, known as "JMC," with the aim of better understanding human disease and elucidating gene functions. For this mission, we constructed a systematic phenotyping platform that analyzes more than 700 items, and conducted phenotype analysis of mouse resources such as the genetically modified mice deposited at the BRC. We also provided a phenotyping platform to the domestic research community. The study found a new phenotype in genetically modified mice and we expect it to be re-evaluated as a new human disease model. Furthermore, we will correlate clinical data of human disease with mouse phenotype information to further enhance the value of mouse resources in Japan and contribute to its development and intellectual infrastructure.