Technology and Development Teams for Mouse Phenotype Analysis develops "Mouse Clinic" which is a phenotype analysis platform for genetically modified mice that systematically examines more than 400 items, aiming to understand the pathology of human diseases and elucidate gene functions. The Team participates in the International Mouse Phenotyping Consortium (IMPC), publishes the results of the phenotype analyses, and develops new technologies on phenotyping analyses.


Team Mission

  • Development of systematic and comprehensive phenotyping platform for mice
  • International contribution through participation in the IMPC
  • Provision of international standardized phenotyping methods to the domestic research community
  • Development of new phenotyping methods
IMPC_logo Japan Mouse Clinic is one of institutional members of IMPC (International Mouse Phenotyping Consortium).
Enter the page "Activity for IMPC" to search phenotype and development information of IMPC Knockout mouse strains.


What's news

2020/08/04 The RIKEN BRC Website was renewed. With this change, we updated the team website.
2020/06/22 A paper on "Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity" that Mr. Miura conducted a genome scan analysis as a collaborator has been published in Nature Immunology. This is a joint research with the Osaka University, Kyushu University, and RIKEN IMS.
2020/05/20 Announcement: On May 20th, RIKEN BioResource Research Center resumed a part of the bioresource deposition/distribution services.
2020/02/26 A research paper on "Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes" that team leader, Dr. Tamura with Dr. Furuse, Dr. Yamada and Dr. Shibuya conducted an imaging and behavioral analysis as a collaborator has been published in Nature Communications. This is a joint research with several research institutes and universities including Osaka University and National Center of Neurology and Psychiatry.
https://www.nature.com/articles/s41467-020-14697-z

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