| Procedure | Immunophenotyping test v.1.0 | ||
|---|---|---|---|
| Pipeline | IMPC_adult_v2-LaterOnset | Screen Age (week) | 16-56w |
| Parameter Group | NKT cell (panel A) | ||
| Strain | Condition 1 | Pipeline(s) | Tested Day (Age) |
|---|---|---|---|
| IMPC_adult_v2-LaterOnset | |||
| C57BL/6NJcl | Late | ♀: 3 ♂: 3 |
2015/11/26 - 2016/08/30 (17.07 - 56.93) |
| Early | ♀: 3 ♂: 3 |
| Parameter | Difference | Supplement |
|---|---|---|
| CD4 NKT | S | |
| CD4 CD25- NKT | NS | |
| CD4 CD25+ NKT | NS | |
| CD4 Central Memory NKT | S | |
| CD4 Effector Memory NKT | S | |
| CD4 Naive NKT | S | |
| CD8 NKT | S | |
| CD8 CD25- NKT | NS | |
| CD8 CD25+ NKT | NS | |
| CD8 Central Memory NKT | NS | |
| CD8 Effector Memory NKT | NS | |
| CD8 Naive NKT | S | |
| DN NKT | NS | |
| DN CD25- NKT | NS | |
| DN CD25+ NKT | NS | |
| DN Central Memory NKT | NS | |
| DN Effector Memory NKT | NS | |
| DN Naive NKT | S | |
| NKT cells (panel A) | S |
| comment |
|---|
| NKT (panel A) was decreased in 56-week-old mice (Late) relative to 16-week-old mice (Early). CD4 NKT and CD4 Effector Memory NKT subtype were decreased in 56-week-old mice (Late) relative to 16-week-old mice (Early). CD4 Central Memory and Naive NKT subtypes were increased in 56-week-old mice (Late) relative to 16-week-old mice (Early). |