| Procedure | Immunophenotyping test v.1.0 | ||
|---|---|---|---|
| Pipeline | IMPC_adult_v2-LaterOnset | Screen Age (week) | 16-56w |
| Parameter Group | NKT cell (panel A) | ||
| Parameter | CD4 Effector Memory NKT | ||
| Strain | Condition 1 | Pipeline(s) | Tested Day (Age) |
|---|---|---|---|
| IMPC_adult_v2-LaterOnset | |||
| C57BL/6NJcl | Late | ♀: 3 ♂: 3 |
2015/11/26 - 2016/08/30 (17.07 - 56.93) |
| Early | ♀: 3 ♂: 3 |
| Factor | df | Bartlett's K2 | p |
|---|---|---|---|
| condition1 | 1 | 1.445204 | 0.229299 |
| sex | 1 | 1.561093 | 0.2115053 |
| Factor | mean | median | SD | SEM | N |
|---|---|---|---|---|---|
| condition1 - sex | |||||
| Early(16w) - Female | 84.6 | 83.06 | 5.72 | 3.3 | 3 |
| Early(16w) - Male | 85.06 | 86.8 | 3.76 | 2.17 | 3 |
| Late(56w) - Female | 78.51 | 80.22 | 4.8 | 2.77 | 3 |
| Late(56w) - Male | 67.69 | 71.19 | 6.24 | 3.6 | 3 |
| Signif. codes ***: <0.001 **: <0.010 *: <0.050 †: <0.100 |
||||||
| Factor | df | Sum Sq. | F value | Pr(>F) | Signif. | |
|---|---|---|---|---|---|---|
| condition1 | 1 | 412.78 | 15.1640 | 0.004583 | ** | |
| sex | 1 | 80.29 | 2.9496 | 0.124229 | ||
| condition1:sex | 1 | 95.43 | 3.5057 | 0.098052 | † | |
| Residuals | 8 | 217.77 | ||||
| Level | Difference | Lower | Upper | Adjusted p |
|---|---|---|---|---|
| Late(56w) - Early(16w) | -11.7 | -18.7 | -4.78 | 0.00458 |
| comment |
|---|
| CD4 EM NKT was significantly decreased in 56-week-old mice (Late) relative to 16-week-old mice (Early) (p<0.01). |