| Procedure | Immunophenotyping test v.1.0 | ||
|---|---|---|---|
| Pipeline | IMPC_adult_v2-LaterOnset | Screen Age (week) | 16-56w |
| Strain | Condition 1 | Pipeline(s) | Tested Day (Age) |
|---|---|---|---|
| IMPC_adult_v2-LaterOnset | |||
| C57BL/6NJcl | Late | ♀: 3 ♂: 3 |
2015/11/26 - 2016/08/30 (17.07 - 56.93) |
| Early | ♀: 3 ♂: 3 |
| Parameter | Difference | Supplement |
|---|---|---|
| Body weight | S | |
| B cell (panel B) | S | |
| Myeloid (panel B) | S | |
| NKT cell (panel A) | S | |
| NKT cell (panel B) | S | |
| NK cells (panel A) | S | |
| NK cell (panel B) | S | |
| Other cells (panel A) | NS | |
| Spleen weight | NS | |
| Spleen weigth/BW | S | |
| T cell (panel A) | S | |
| T cell (panel B) | S |
| comment |
|---|
| Body weight was increased in 56-week-old mice (Late) relative to 16-week-old mice (Early). NK cells, NKT cells, Eosinophils and Monocytes were decreased in 56-week-old mice (Late) relative to 16-week-old mice (Early). B cells was increased in 56-week-old mice (Late) relative to 16-week-old mice (Early). Effector Memory T subtypes were increased in 56-week-old mice (Late) relative to 16-week-old mice (Early). CD4 and DN (CD4-CD8-) Central Memory T subtypes were decreased in 56-week-old mice (Late) relative to 16-week-old mice (Early). |