| Procedure | Electrocardiogram (ECG) v１ | ||
|---|---|---|---|
| Pipeline | IMPC_adult_v2-LaterOnset | Screen Age (week) | 12-52w |
| Strain | Condition 1 | Pipeline(s) | Tested Day (Age) |
|---|---|---|---|
| IMPC_adult_v2-LaterOnset | |||
| C57BL/6NJcl | Late | ♀: 4 ♂: 4 |
2015/10/27 - 2016/08/02 (12.64 - 52.79) |
| Early | ♀: 5 ♂: 5 |
| Parameter | Difference | Supplement |
|---|---|---|
| Coefficient of variation (CV) | NS | |
| Heart rate (HR) | S | |
| JT interval | S | |
| PR interval | S | |
| QRS interval | S | |
| QT interval | S | |
| QTc | S | |
| RR interval | S | |
| Mean R amplitude | S | |
| Mean SR amplitude | NS | |
| Tpeak Tend interval | S |
| comment |
|---|
| Heart rate (HR), Mean R amplitude and QTc were decreased in 52-week-old mice (Late) relative to 12-week-old mice (Early). JT interval, PR interval, QRS interval, RR interval and Tpeak Tend interval were increased in 52-week-old mice (Late) relative to 12-week-old mice (Early). QT interval was increased in 52-week-old mice (Late) relative to 12-week-old mice (Early) in only male. |