| Procedure | Electrocardiogram (ECG) v１ | ||
|---|---|---|---|
| Pipeline | IMPC_adult_v2-LaterOnset | Screen Age (week) | 12-52w |
| Parameter | Heart rate (HR) | ||
| Strain | Condition 1 | Pipeline(s) | Tested Day (Age) |
|---|---|---|---|
| IMPC_adult_v2-LaterOnset | |||
| C57BL/6NJcl | Late | ♀: 4 ♂: 4 |
2015/10/27 - 2016/08/02 (12.64 - 52.79) |
| Early | ♀: 5 ♂: 5 |
| Factor | df | Bartlett's K2 | p |
|---|---|---|---|
| condition1 | 1 | 0.3615481 | 0.5476477 |
| sex | 1 | 0.6397273 | 0.4238096 |
| Factor | mean | median | SD | SEM | N |
|---|---|---|---|---|---|
| condition1 - sex | |||||
| Early(12w) - Female | 702.3 | 718 | 35.73 | 15.98 | 5 |
| Early(12w) - Male | 704.22 | 705.7 | 20.5 | 9.17 | 5 |
| Late(52w) - Female | 666.8 | 667.4 | 15.9 | 7.95 | 4 |
| Late(52w) - Male | 647.17 | 661.05 | 47.18 | 23.59 | 4 |
| Signif. codes ***: <0.001 **: <0.010 *: <0.050 †: <0.100 |
||||||
| Factor | df | Sum Sq. | F value | Pr(>F) | Signif. | |
|---|---|---|---|---|---|---|
| condition1 | 1 | 9516.2 | 9.3668 | 0.008471 | ** | |
| sex | 1 | 263.7 | 0.2596 | 0.618336 | ||
| condition1:sex | 1 | 515.8 | 0.5077 | 0.487857 | ||
| Residuals | 14 | 14223.3 | ||||
| Level | Difference | Lower | Upper | Adjusted p |
|---|---|---|---|---|
| Late(52w) - Early(12w) | -46.3 | -78.7 | -13.8 | 0.00847 |
| comment |
|---|
| HR was significantly decreased in 52-week-old mice (Late) relative to 12-week-old mice (Early) (p<0.01). |