Procedure Electrocardiogram (ECG) v1
Pipeline IMPC_adult_v2-LaterOnset Screen Age (week) 12-52w
Parameter Mean R amplitude
Strain Condition 1 Pipeline(s) Tested Day
(Age)
IMPC_adult_v2-LaterOnset
C57BL/6NJcl Late ♀: 4  ♂: 4 2015/10/27 - 2016/08/02
(12.64 - 52.79)
Early ♀: 5  ♂: 5
Raw Data

Bartlett test result
Factor df Bartlett's K2 p
condition1 1 0.007560545 0.9307101
sex 1 0.2028970 0.6523926

Summary statistics
Factor mean median SD SEM N
condition1 - sex
Early(12w) - Female 0.86 0.78 0.22 0.1 5
Early(12w) - Male 1.09 1.14 0.26 0.12 5
Late(52w) - Female 0.62 0.64 0.28 0.14 4
Late(52w) - Male 0.73 0.73 0.27 0.14 4

ANOVA result
Signif. codes ***: <0.001
**: <0.010
*: <0.050
†: <0.100
Factor df Sum Sq. F value Pr(>F) Signif.
condition1 1 0.39416 5.9941 0.02814 *
sex 1 0.13682 2.0806 0.17118
condition1:sex 1 0.01249 0.1899 0.66967
Residuals 14 0.92061

Tukey multiple comparisons of means
Factor: condition1
Level Difference Lower Upper Adjusted p
Late(52w) - Early(12w) -0.298 -0.559 -0.0369 0.0281



FM_02_U_barchart.png

comment
Mean R amplitude was significantly decreased in 52-week-old mice (Late) relative to 12-week-old mice (Early) (p<0.05).