Procedure | Immunophenotyping test v.1.0 | ||
---|---|---|---|
Pipeline | IMPC_adult_v2-LaterOnset | Screen Age (week) | 16-56w |
Parameter | Spleen weigth/BW |
Strain | Condition 1 | Pipeline(s) | Tested Day (Age) |
---|---|---|---|
IMPC_adult_v2-LaterOnset | |||
C57BL/6NJcl | Late | ♀: 3 ♂: 3 |
2015/11/26 - 2016/08/30 (17.07 - 56.93) |
Early | ♀: 3 ♂: 3 |
Factor | df | Bartlett's K2 | p |
---|---|---|---|
condition1 | 1 | 1.631888 | 0.2014421 |
sex | 1 | 1.504023 | 0.2200535 |
Factor | mean | median | SD | SEM | N |
---|---|---|---|---|---|
condition1 - sex | |||||
Early(16w) - Female | 4.87 | 4.9 | 0.15 | 0.09 | 3 |
Early(16w) - Male | 2.77 | 3 | 0.49 | 0.28 | 3 |
Late(56w) - Female | 2.6 | 2.4 | 0.53 | 0.31 | 3 |
Late(56w) - Male | 1.6 | 1.6 | 0.1 | 0.06 | 3 |
Signif. codes ***: <0.001 **: <0.010 *: <0.050 : <0.100 |
||||||
Factor | df | Sum Sq. | F value | Pr(>F) | Signif. | |
---|---|---|---|---|---|---|
condition1 | 1 | 8.8408 | 63.527 | 4.485e-05 | *** | |
sex | 1 | 7.2075 | 51.790 | 9.276e-05 | *** | |
condition1:sex | 1 | 0.9075 | 6.521 | 0.03398 | * | |
Residuals | 8 | 1.1133 | ||||
Level | Difference | Lower | Upper | Adjusted p |
---|---|---|---|---|
Late(56w) - Early(16w) | -1.72 | -2.21 | -1.22 | 4.49e-05 |
Level | Difference | Lower | Upper | Adjusted p |
---|---|---|---|---|
Male - Female | -1.55 | -2.05 | -1.05 | 9.28e-05 |
Level | Difference | Lower | Upper | Adjusted p |
---|---|---|---|---|
Late(56w):Female - Early(16w):Female | -2.267 | -3.242 | -1.2912 | 3.36e-04 |
Early(16w):Male - Early(16w):Female | -2.100 | -3.075 | -1.1246 | 5.71e-04 |
Late(56w):Male - Early(16w):Female | -3.267 | -4.242 | -2.2912 | 2.35e-05 |
Early(16w):Male - Late(56w):Female | 0.167 | -0.809 | 1.1421 | 9.45e-01 |
Late(56w):Male - Late(56w):Female | -1.000 | -1.975 | -0.0246 | 4.46e-02 |
Late(56w):Male - Early(16w):Male | -1.167 | -2.142 | -0.1912 | 2.09e-02 |
comment |
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Spleen weight/BW was significantly decreased in 56-week-old mice (Late) relative to 16-week-old mice (Early) (p<0.001) in female. Spleen weight/BW was significantly decreased in 56-week-old mice (Late) relative to 16-week-old mice (Early) (p<0.05) in male. |