Procedure Immunophenotyping test v.1.0
Pipeline IMPC_adult_v2-LaterOnset Screen Age (week) 16-56w
Parameter Group T cell (panel A)
Strain Condition 1 Pipeline(s) Tested Day
(Age)
IMPC_adult_v2-LaterOnset
C57BL/6NJcl Late ♀: 3  ♂: 3 2015/11/26 - 2016/08/30
(17.07 - 56.93)
Early ♀: 3  ♂: 3
Parameter Difference Supplement
CD4 T NS
CD4 CD25- T NS
CD4 Central Memory T S
CD4 Effector Memory T S
CD4 Naive T NS
CD8 T S
CD8 CD25- T S
CD8 CD25+ T S
CD8 Central Memory T S
CD8 Effector Memory T S
CD8 Naive T S
DN T S
DN CD25- T NS
DN CD25+ T NS
DN Central Memory T S
DN Effector Memory T S
DN Naive T S
T cells (panel A) NS
Treg NS
comment
Effector Memory T subtypes were increased in 56-week-old mice (Late) relative to 16-week-old mice (Early).
CD4 and DN (CD4-CD8-) Central Memory T subtypes were decreased in 56-week-old mice (Late) relative to 16-week-old mice (Early).