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LCNS mutant strains.

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Total of 35 mutant strains in ten LCNS sequences are available as of November 18, 2008. (Ref. Sakuraba et al. Mammalian Genome, 2008.)

*1 Mutation is shown by the base change and the position in the mouse genomic sequence that is available in the Mouse/UCSC column.

*2 LCNS348 is not in the Supplementary Table 1 of the reference because this sequence disappeared in the assembled mouse genome database, mm9. LCNS348 was in the mouse (mm4) database and still is in the human (hg18) database and suffice the criteria defined by the reference.When mutations were screened, the LCNS348 sequence was indeed repeatedly amplified by the PCR primer pair as shown in the reference from many G1 mouse genomic DNA samples. Thus, LCNS348 does exitst in human and many other vertebrate species as shown in 348/hg18, and in the mosue genome (348/mm4) as well confirmed by the PCR amplification.

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