| Procedure | Immunophenotyping test v.1.0 | ||
|---|---|---|---|
| Pipeline | IMPC_adult_v2-LaterOnset | Screen Age (week) | 16-56w |
| Parameter Group | T cell (panel A) | ||
| Parameter | CD8 T | ||
| Strain | Condition 1 | Pipeline(s) | Tested Day (Age) |
|---|---|---|---|
| IMPC_adult_v2-LaterOnset | |||
| C57BL/6NJcl | Late | ♀: 3 ♂: 3 |
2015/11/26 - 2016/08/30 (17.07 - 56.93) |
| Early | ♀: 3 ♂: 3 |
| Factor | df | Bartlett's K2 | p |
|---|---|---|---|
| condition1 | 1 | 1.148127 | 0.2839416 |
| sex | 1 | 1.500691 | 0.2205650 |
| Factor | mean | median | SD | SEM | N |
|---|---|---|---|---|---|
| condition1 - sex | |||||
| Early(16w) - Female | 49.81 | 49.62 | 2.22 | 1.28 | 3 |
| Early(16w) - Male | 48.43 | 47.64 | 1.75 | 1.01 | 3 |
| Late(56w) - Female | 39.82 | 39.63 | 1.02 | 0.59 | 3 |
| Late(56w) - Male | 44.4 | 45.47 | 3.09 | 1.78 | 3 |
| Signif. codes ***: <0.001 **: <0.010 *: <0.050 †: <0.100 |
||||||
| Factor | df | Sum Sq. | F value | Pr(>F) | Signif. | |
|---|---|---|---|---|---|---|
| condition1 | 1 | 147.420 | 31.7421 | 0.0004904 | *** | |
| sex | 1 | 7.680 | 1.6536 | 0.2344340 | ||
| condition1:sex | 1 | 26.582 | 5.7235 | 0.0436933 | * | |
| Residuals | 8 | 37.155 | ||||
| Level | Difference | Lower | Upper | Adjusted p |
|---|---|---|---|---|
| Late(56w) - Early(16w) | -7.01 | -9.88 | -4.14 | 0.00049 |
| Level | Difference | Lower | Upper | Adjusted p |
|---|---|---|---|---|
| Late(56w):Female - Early(16w):Female | -9.99 | -15.62 | -4.352 | 0.00209 |
| Early(16w):Male - Early(16w):Female | -1.38 | -7.01 | 4.258 | 0.86042 |
| Late(56w):Male - Early(16w):Female | -5.41 | -11.04 | 0.225 | 0.05987 |
| Early(16w):Male - Late(56w):Female | 8.61 | 2.98 | 14.245 | 0.00527 |
| Late(56w):Male - Late(56w):Female | 4.58 | -1.06 | 10.212 | 0.11674 |
| Late(56w):Male - Early(16w):Male | -4.03 | -9.67 | 1.602 | 0.17899 |
| comment |
|---|
| CD8T was significantly decreased in 56-week-old mice (Late) relative to 16-week-old mice (Early) (p<0.01) in only female. |