Procedure | Grip Strength | ||
---|---|---|---|
Pipeline | IMPC_adult_v2-LaterOnset | Screen Age (week) | 9-49w |
Parameter | Forelimb grip strength normalised against body weight |
Strain | Condition 1 | Pipeline(s) | Tested Day (Age) |
---|---|---|---|
IMPC_adult_v2-LaterOnset | |||
C57BL/6NJcl | Late | ♀: 11 ♂: 9 |
2015/10/06 - 2016/07/12 (9.36 - 49.93) |
Early | ♀: 14 ♂: 13 |
Factor | df | Bartlett's K2 | p |
---|---|---|---|
condition1 | 1 | 0.5492389 | 0.4586288 |
sex | 1 | 1.980227 | 0.1593665 |
Factor | mean | median | SD | SEM | N |
---|---|---|---|---|---|
condition1 - sex | |||||
Early(9w) - Female | 3.15 | 3.01 | 0.75 | 0.2 | 14 |
Early(9w) - Male | 2.86 | 2.34 | 1.1 | 0.31 | 13 |
Late(49w) - Female | 2.4 | 2.36 | 0.75 | 0.23 | 11 |
Late(49w) - Male | 1.62 | 1.37 | 0.64 | 0.21 | 9 |
Signif. codes ***: <0.001 **: <0.010 *: <0.050 : <0.100 |
||||||
Factor | df | Sum Sq. | F value | Pr(>F) | Signif. | |
---|---|---|---|---|---|---|
condition1 | 1 | 10.9189 | 15.2578 | 0.0003267 | *** | |
sex | 1 | 2.8938 | 4.0438 | 0.0506315 | | |
condition1:sex | 1 | 0.6712 | 0.9379 | 0.3382323 | ||
Residuals | 43 | 30.7721 | ||||
Level | Difference | Lower | Upper | Adjusted p |
---|---|---|---|---|
Late(49w) - Early(9w) | -0.96 | -1.46 | -0.456 | 0.000393 |
comment |
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Forelimb grip strength normalised against body weight was significantly decreased in 49-week-old mice (Late) relative to 9-week-old mice (Early) (p<0.01). |