理研ENU-based gene-driven mutagenesisの利用案内へ
公開中の変異マウス系統.
分与希望の系統は下記リストからBRC Noを確認のうえ、実験動物開発室のホームページから申込ください。なお、ENU変異系統マウスは、遺伝子組換えマウスではありません。
問い合わせ先:
| BRC No. | Strain Name of G1 | Locus | Gene | Allele | Mutation Info. | Base subst. | Mutation site ±10bp context | Phenotype Info. | References and Comments |
| RBRC-02324 | M101393 | MMU08 E2 | Disc1 | Rgsc01393 | Gln > Leu | A→T | GTAGCCCCTCAGAGGCGGCGG | Major depression-like | "left">[2], a backcross line of RBRC-GD0047 to C57BL/6J |
| RBRC-02325 | M101390 | MMU08 E2 | Disc1 | Rgsc01390 | Leu > Pro | T→C | AAGCCTTTTCTCAAGAGCTCC | Schizophorenia-like | [2], a backcross line of RBRC-GD0048 to C57BL/6J |
| RBRC-GSC0224 | M101116 | MMU05 A3 | MFCS1 | Rgsc01116 | cis element | T→C | TGATGATCCATAAATTGTTGG | dominant preaxial polydactyly | [1] |
| RBRC-GSC0225 | M101117 | MMU05 A3 | MFCS1 | Rgsc01117 | cis element | T→C | TAACTGTTGCTATGTGTTAAT | no phenotypes found yet | [1] |
| RBRC-GSC0226 | M101155 | MMU05 A3 | MFCS1 | Rgsc01155 | cis element | T→A | GATTTCATAATGAACTCCAGA | ||
| RBRC-GSC0227 | M101192 | MMU05 A3 | MFCS1 | Rgsc01192 | cis element | T→A | AGTACTTTCATAATAAAAGTA | no phenotypes found yet | [1] |
| RBRC-GSC0228 | M101197 | MMU05 A3 | MFCS1 | Rgsc01197 | cis element | T→A | ATCAGATTTATTTTGTATGTT | ||
| RBRC-GSC0229 | M101198 | MMU05 A3 | MFCS1 | Rgsc01198 | cis element | T→C | AGTGGGGAAAATATCTCACCA | ||
| RBRC-GD000009 | M100202 | MMU07 E1 | Tyr | Rgsc00202 | Promoter region | A→T | tagtgtcgaaagtagtacaga | no phenotypes found yet | |
| RBRC-GD000010 | M102008 | MMU07 E1 | Tyr | Rgsc02008 | intron | G→A | CTTCAAAGTTGTTATTAAACA | ||
| RBRC-GD000011 | M102005 | MMU06 A3 | Smo | Rgsc02005 | intron | C→A | ATACTGAAGGCAGCTGAGTCC | ||
| RBRC-GD000012 | M102006 | MMU07 D2 | Blm | Rgsc02006 | synonymous | C→T | CAGTGCAGGGCGACTCCTGCC | ||
| RBRC-GD000013 | M102007 | MMU11 C | Hoxb1 | Rgsc02007 | 3' flanking | T→C | GGATTAAGATTAAGGGTTGGT | ||
| RBRC-GD000014 | M100683 | MMU10 D3 | Avpr1a | Rgsc00683 | Ser > Asn | G→A | GACAGCATGAGTTTCCCGCGA | ||
| RBRC-GD000015 | M100727 | MMU05 B1 | Hdh | Rgsc00727 | Phe > Leu | T→C | GCTCAAGTCGTTTCAGCAGCA | ||
| RBRC-GD000016 | M102010 | MMU07 E1 | Tyr | Rgsc02010 | intron | A→T | AAAAATCATGATTTCAAGTAA | ||
| RBRC-GD000017 | M100742 | MMU05 G3 | Brca2 | Rgsc00742 | Ser > Pro | T→C | AGGAAATGCCTCATATGAACA | ||
| RBRC-GD000018 | M100840 | MMU04 A2 | Nbn | Rgsc00840 | Ile > Thr | T→C | GGGATGGACATAGAACTCAAC | ||
| RBRC-GD000019 | M100841 | MMU01 C3 | Bard1 | Rgsc00841 | Pro > Ser | C→T | TAGCCAAATACCAGTTATGGA | ||
| RBRC-GD000020 | M100938 | MMU01 H4 | Psen2 | Rgsc00938 | splicing donor | G→A | ACGGGCAGCTGTGAGTTGGGG | ||
| RBRC-GD000021 | M102014 | MMU07 D2 | Blm | Rgsc02014 | intron | T→C | TCATATTTATTGTGCTTTCTT | ||
| RBRC-GD000022 | M101099 | MMU07 A3 | Dmrtc2 | Rgsc01099 | Thr > Ile | C→T | CATGGGGTCACAGCCCATCTC | ||
| RBRC-GD000023 | M101223 | MMU06 A3 | Smo | Rgsc01223 | intron | T→A | TGAGATTTTTTTTATATGTCA | ||
| RBRC-GD000024 | M101204 | MMU05 A3 | Shh | Rgsc01204 | synonymous | A→C | CCGACATCATATTTAAGGATG | ||
| RBRC-GD000025 | M101113 | MMU01 C3 | Bard1 | Rgsc01113 | Cys > Ser | T→A | AGAACCTGAATGTTCTGGAAG | ||
| RBRC-GD000026 | M101114 | MMU16 B1 | Adipoq | Rgsc01114 | promoter region | A→T | GCCTGGAAACAGGATGGCTTG | ||
| RBRC-GD000027 | M101171 | MMU16 B1 | Adipoq | Rgsc01171 | 3' flanking | T→C | ATAATGTAAATATGAAATACA | ||
| RBRC-GD000028 | M101131 | MMU04 A2 | Nbn | Rgsc01131 | Leu > Stop | T→A | AAGCCAGAGTTGGCAGTTCAA | ||
| RBRC-GD000029 | M102003 | MMU05 A3 | Shh | Rgsc02003 | synonymous | A→G | AGAGGTGCAAAGACAAGTTAA | ||
| RBRC-GD000030 | M101154 | MMU05 G3 | Brca2 | Rgsc01154 | Arg > His | G→A | ATAAACTCACGTAAGGATAGT | ||
| RBRC-GD000031 | M102013 | MMU05 A3 | Shh | Rgsc02013 | intron | G→T | TCCTGGGCCTGTGGTTGGTGG | ||
| RBRC-GD000032 | M100772 | MMU16 B1 | Adipoq | Rgsc00772 | Arg > Gly | A→G | AACCCCTGGCAGGAAAGGAGA | ||
| RBRC-GD000033 | M102012 | MMU16 B1 | Adipoq | Rgsc02012 | synonymous | C→A | TGAAGGGCCACGGGGCTTCCC | ||
| RBRC-GD000034 | M101179 | MMU05 G3 | Brca2 | Rgsc01179 | Tyr > His | T→C | TATAAATGAATATTGTGTTCA | ||
| RBRC-GD000035 | M102015 | MMU04 A2 | Nbn | Rgsc02015 | intron | C→A | AGTGCTTCCTCCCATTTCCAG | ||
| RBRC-GD000036 | M100863 | MMU06 A3 | Smo | Rgsc00863 | intron | T→C | AATTTTTTAATGTGGCTACTA | ||
| RBRC-GD000037 | M101228 | MMU13 B3 | Ptch1 | Rgsc01228 | intron | T→C | CTTCCCCCAATCGTTCTGCTT | ||
| RBRC-GD000038 | M101207 | MMU05 G3 | Brca2 | Rgsc01207 | Asp > Glu | T→A | CTTCAGGTGATGTCTGCATAA | ||
| RBRC-GD000039 | M101296 | MMU17 C | Polh | Rgsc01296 | Ala > Val | C→T | AACATGTGGGCGGATGATGCT | ||
| RBRC-GD000040 | M101258 | MMU17 C | Polh | Rgsc01258 | synonymous | G→A | GACTTCAAAAGTTACAAGGTC | ||
| RBRC-GD000041 | M101279 | MMU17 C | Polh | Rgsc01279 | intron | C→T | TGCTGCTTTTCGTGGCTAAGC | ||
| RBRC-GD000042 | M101287 | MMU05 B1 | Hdh | Rgsc01287 | intron | T→C | acttaagctatctcacagtct | ||
| RBRC-GD000043 | M101285 | MMU05 B1 | Hdh | Rgsc01285 | Ala > Ser | G→T | CCTGACCAGTGCTGCTACTGA | ||
| RBRC-GD000044 | M101337 | MMU05 B1 | Hdh | Rgsc01337 | Phe > Ser | T→C | CCAGAGTCGTTCTTCAGCAGA | ||
| RBRC-GD000045 | M101332 | MMU07 A3 | Dmrtc2 | Rgsc01332 | intron | T→A | tcattttgagtttatctttgt | ||
| RBRC-GD000046 | M101392 | MMU08 E2 | Disc1 | Rgsc01392 | synonymous | A→G | AGCAGTCCCAACACTCACAGT | ||
| RBRC-GD000047 | M101393 | MMU08 E2 | Disc1 | Rgsc01393 | Gln > Leu | A→T | GTAGCCCCTCAGAGGCGGCGG | Majordepression-like | [2], The original G1 line of RBRC02324 |
| RBRC-GD000048 | M101390 | MMU08 E2 | Disc1 | Rgsc01390 | Leu > Pro | T→C | AAGCCTTTTCTCAAGAGCTCC | Schizophorenia-like | [2], The original G1 line of RBRC02325 |
| RBRC-GD000049 | M100034 | MMU11 B4 | Srr | Rgsc00034 | intron | G→A | gtccactaccggtaaataaac | ||
| RBRC-GD000050 | M101404 | MMU02 B | 2900010J23Rik | Rgsc01404 | Ile > Thr | T→C | AGCTCTGACATTAAGAAACTG | ||
| RBRC-GD000051 | M101397 | MMU02 B | 2900010J23Rik | Rgsc01397 | synonymous | G→T | CACAGATGCTGCTGGGGAAGC | ||
| RBRC-GD000052 | M101402 | MMU02 B | 2900010J23Rik | Rgsc01402 | Ile > Val | A→G | ATTCCCCATGATTGATGAGAA | ||
| RBRC-GD000053 | M101403 | MMU02 B | 2900010J23Rik | Rgsc01403 | intron | T→C | ctctgaatagtaatccaccct | ||
| RBRC-GD000054 | M101421 | MMU02 B | 2900010J23Rik | Rgsc01421 | Leu > Ser | T→C | GAGGAGGCCTTGAGCTCTGAC | ||
| RBRC-GD000055 | M101412 | MMU05 B1 | Hdh | Rgsc01412 | intron | T→A | attgttaagatgattaattga | ||
| RBRC-GD000056 | M101481 | MMU03 A1 | LCNS124 | Rgsc01481 | noncoding | T→C | TGCAAACATATGCGCTAAGCT | [3] | |
| RBRC-GD000057 | M101483 | MMU02 C3 | LCNS112 | Rgsc01483 | noncoding | A→T | ACATTTAAATAGAAGCACTGG | [3] | |
| RBRC-GD000058 | M101428 | MMU05 B1 | Hdh | Rgsc01428 | Gln > His | G→T | ccctggcacagtacctggtgg | ||
| RBRC-GD000059 | M101456 | MMU05 B1 | Hdh | Rgsc01456 | intron | A→T | tagaatttagatctataggta | ||
| RBRC-GD000060 | M101082 | MMU02 C3 | LCNS112 | Rgsc01082 | noncoding | T→C | TCAGAATGCGTAAACTTGCAA | [3] | |
| RBRC-GD000061 | M101482 | MMU02 C3 | LCNS112 | Rgsc01482 | noncoding | A→G | ATGGGTTGATAAGTTAATTTA | [3] | |
| RBRC-GD000062 | M101484 | MMU13 A2 | LCNS348 | Rgsc01484 | noncoding | A→C | TATTCTTTACAGTCTGTTGAC | [3] | |
| RBRC-GD000063 | M101509 | MMU08 A2 | LCNS242 | Rgsc01509 | noncoding | T→A | AAAACTAATATGTCACTGTCA | [3] | |
| RBRC-GD000064 | M101505 | MMU14 A3 | LCNS354 | Rgsc01505 | noncoding | A→T | TGGGTTTCGCAGAGATTTCCC | [3] | |
| RBRC-GD000065 | M101507 | MMU14 A3 | LCNS354 | Rgsc01507 | noncoding | A→T | GCTGAGAACAAAGTAAATTTA | [3] | |
| RBRC-GD000066 | M101508 | MMU14 A3 | LCNS354 | Rgsc01508 | noncoding | A→G | TCCCATAAAAAAGCAAAGGAC | [3] | |
| RBRC-GD000067 | M101540 | MMU04 A2 | Nbn | Rgsc01540 | intron | C→T | acaactttctcttgaataagc | ||
| RBRC-GD000068 | M101549 | MMU02 C3 | LCNS112 | Rgsc01549 | noncoding | A→T | TTAATGAGCTATAGTTAAATT | [3] | |
| RBRC-GD000069 | M101550 | MMU13 A2 | LCNS348 | Rgsc01550 | noncoding | A→T | TAATTTGCACAGCACTTAAAT | [3] | |
| RBRC-GD000070 | M101548 | MMU13 A2 | LCNS348 | Rgsc01548 | noncoding | G→T | TAAGGGAATGGTGGAAAGGAT | [3] | |
| RBRC-GD000071 | M101608 | MMU14 A3 | LCNS354 | Rgsc01608 | noncoding | T→A | CAACTACGCATAATGTACCGA | [3] | |
| RBRC-GD000072 | M101021 | MMU14 A3 | LCNS354 | Rgsc01021 | noncoding | A→C | AATAAGATTCAGCTTGACTTC | [3] | |
| RBRC-GD000073 | M101826 | MMU08 E2 | Disc1 | Rgsc01826 | synonymous | A→T | GCCTTGATGCACCCTGGAACA | ||
| RBRC-GD000074 | M101728 | MMU14 A3 | LCNS354 | Rgsc01728 | noncoding | T→A | CAGTGAACTTTAATGGGATTT | [3] | |
| RBRC-GD000075 | M101725 | MMU04 C4 | LCNS161 | Rgsc01725 | noncoding | A→G | AATGTGACAGACTGAGAGAAG | [3] | |
| RBRC-GD000076 | M101727 | MMU04 C4 | LCNS161 | Rgsc01727 | noncoding | T→C | AGGGCAAAACTGAGAAATGTG | [3] | |
| RBRC-GD000077 | M101724 | MMU04 C4 | LCNS161 | Rgsc01724 | noncoding | A→G | ACCAACCCCAAGTTTATTTAG | [3] | |
| RBRC-GD000078 | M101731 | MMU04 C4 | LCNS161 | Rgsc01731 | noncoding | A→T | TCAATGAAAGATCATCAGCCA | [3] | |
| RBRC-GD000079 | M101726 | MMU18 E4 | LCNS418 | Rgsc01726 | noncoding | T→A | GCATATTTGATGGAGGAATAA | [3] | |
| RBRC-GD000080 | M101729 | MMU18 E4 | LCNS418 | Rgsc01729 | noncoding | T→A | CTCTAACAAATAGGGACATCA | [3] | |
| RBRC-GD000081 | M101830 | MMU04 A3 | LCNS152 | Rgsc01830 | noncoding | T→C | TGCTCATTACTCTTGAGCTAA | [3] | |
| RBRC-GD000082 | M101827 | MMU04 A3 | LCNS152 | Rgsc01827 | noncoding | T→A | TGTTAGAATTTGAAATGTAGG | [3] | |
| RBRC-GD000083 | M101831 | MMU04 A3 | LCNS152 | Rgsc01831 | noncoding | T→G | GGGCCACAGATGAGCTCAGTG | [3] | |
| RBRC-GD000084 | M101240 | MMU11 A3 | LCNS276 | Rgsc01240 | noncoding | A→G | GCAATGAATGACAGTGGAAAT | [3] | |
| RBRC-GD000085 | M101485 | MMU14 A3 | LCNS354 | Rgsc01485 | noncoding | G→A | ATTGTAACCTGTTTTTAAAGC | [3] | |
| RBRC-GD000086 | M101828 | MMU14 A3 | LCNS354 | Rgsc01828 | noncoding | C→T | GATTTGACAACATCATATTAA | [3] | |
| RBRC-GD000087 | M101832 | MMU18 A1 | LCNS403 | Rgsc01832 | noncoding | T→C | CTCCTCTCAGTAGCTGACTTT | [3] | |
| RBRC-GD000088 | M101829 | MMU04 A2 | Nbn | Rgsc01829 | Cys > Arg | T→C | ttagACTATATGTGCACTCAT | ||
| RBRC-GD000089 | M100673 | MMU04 A2 | Nbn | Rgsc00673 | Ile > Asn | T→A | TGTGCACTCATTTGTGGACGT | ||
| RBRC-GD000090 | M102035 | MMU04 C4 | LCNS161 | Rgsc02035 | noncoding | T→C | ATCAGCCACATTATCAGTGTT | [3] | |
| RBRC-GD000091 | M102036 | MMU04 C4 | LCNS161 | Rgsc02036 | noncoding | A→T | CCTGCTGTGAACAATCTGTAA | [3] | |
| RBRC-GD000092 | M102033 | MMU11 A3 | LCNS276 | Rgsc02033 | noncoding | A→T | CTACAAATCCAATTACAGATT | [3] | |
| RBRC-GD000093 | M102038 | MMU11 A3 | LCNS276 | Rgsc02038 | noncoding | A→T | TTGGAGACTCAGAGGCAGGTG | [3] | |
| RBRC-GD000094 | M102031 | MMU11 A3 | LCNS276 | Rgsc02031 | noncoding | T→A | CAGGTGATAATGAAACTGATA | [3] | |
| RBRC-GD000095 | M102034 | MMU18 E4 | LCNS418 | Rgsc02034 | noncoding | T→C | CAGTCAGAAGTAATTTAACTT | [3] | |
| RBRC-GD000096 | M102032 | MMU18 E4 | LCNS418 | Rgsc02032 | noncoding | A→C | TTGTAACTTCAGTGTTGTAGC | [3] | |
| RBRC-GD000097 | M101873 | MMU11 B4 | Srr | Rgsc01873 | intron | G→A | tttttcgaatgtaacctacta | ||
| RBRC-GD000098 | M101874 | MMU11 B4 | Srr | Rgsc01874 | 3' UTR | A→T | ttgtctctagatgaaaatttt | ||
| RBRC-GD000099 | M101872 | MMU11 B4 | Srr | Rgsc01872 | Tyr > stop | T→A | gccaacagTATGCAACCCAGC | Schizophorenia-like | [4] |
| RBRC-GD000100 | M101875 | MMU11 B4 | Srr | Rgsc01875 | 3' UTR | A→T | ccctttaaaaattatgttcaa | ||
| RBRC-GD000101 | M101916 | MMU11 B4 | Srr | Rgsc01916 | putative splicing | G→A | AAACTGGAAGgtacataactt | ||
| RBRC-GD000102 | M101917 | MMU11 B4 | Srr | Rgsc01917 | intron | T→A | ttgttagaaatgcaccattta | ||
| RBRC-GD000103 | M101918 | MMU11 B4 | Srr | Rgsc01918 | Ile > Ile | T→A | GAGGCTTAATTCCTGACACGC | ||
| RBRC-GD000104 | M101919 | MMU11 B4 | Srr | Rgsc01919 | intron | A→G | tagtgtcgaaagtagtacaga |
参考文献および追加情報:
2008.8.26開設
Copyright(C)2008-2010 RIKEN BioResource Center, Japan. All rights reserved.