Procedure | Intraperitoneal glucose tolerance test (IPGTT) | ||
---|---|---|---|
Pipeline | IMPC_adult_v2-LaterOnset | Screen Age (week) | 13-53w |
Parameter | Body Weight |
Strain | Condition 1 | Pipeline(s) | Tested Day (Age) |
---|---|---|---|
IMPC_adult_v2-LaterOnset | |||
C57BL/6NJcl | Late | ♀: 7 ♂: 7 |
2015/11/05 - 2016/08/09 (13.64 - 53.93) |
Early | ♀: 14 ♂: 13 |
Factor | df | Bartlett's K2 | p |
---|---|---|---|
condition1 | 1 | 9.692607 | 0.001850108 |
sex | 1 | 0.4033934 | 0.525342 |
Factor | mean | median | SD | SEM | N |
---|---|---|---|---|---|
condition1 - sex | |||||
Early(13w) - Female | 20.9 | 20.4 | 1.78 | 0.48 | 14 |
Early(13w) - Male | 27.21 | 27.9 | 3.28 | 0.91 | 13 |
Late(53w) - Female | 33.94 | 30.9 | 8.49 | 3.21 | 7 |
Late(53w) - Male | 44.5 | 46.1 | 4.5 | 1.7 | 7 |
Signif. codes ***: <0.001 **: <0.010 *: <0.050 : <0.100 |
||||||
Factor | df | Sum Sq. | F value | Pr(>F) | Signif. | |
---|---|---|---|---|---|---|
condition1 | 1 | 2112.83 | 107.9097 | 1.609e-12 | *** | |
sex | 1 | 616.68 | 31.4959 | 2.105e-06 | *** | |
condition1:sex | 1 | 41.60 | 2.1247 | 0.1534 | ||
Residuals | 37 | 724.45 | ||||
Level | Difference | Lower | Upper | Adjusted p |
---|---|---|---|---|
Late(53w) - Early(13w) | 15.3 | 12.3 | 18.2 | 9.75e-13 |
Level | Difference | Lower | Upper | Adjusted p |
---|---|---|---|---|
Male - Female | 7.76 | 4.96 | 10.6 | 2.11e-06 |
comment |
---|
Body Weight was significantly increased in 53-week-old mice (Late) relative to 13-week-old mice (Early) (p<0.001). |