Procedure Immunophenotyping test v.1.0
Pipeline IMPC_adult_v2-LaterOnset Screen Age (week) 16-56w
Parameter Group NK cell (panel B)
Parameter CD11b+ Ly6C- NK
Strain Condition 1 Pipeline(s) Tested Day
(Age)
IMPC_adult_v2-LaterOnset
C57BL/6NJcl Late ♀: 3  ♂: 3 2015/11/26 - 2016/08/30
(17.07 - 56.93)
Early ♀: 3  ♂: 3
Raw Data

Bartlett test result
Factor df Bartlett's K2 p
condition1 1 0.2812892 0.5958574
sex 1 0.03005536 0.8623647

Summary statistics
Factor mean median SD SEM N
condition1 - sex
Early(16w) - Female 34.82 34.01 4.3 2.48 3
Early(16w) - Male 29.6 30.48 1.87 1.08 3
Late(56w) - Female 23.41 25.12 3.75 2.16 3
Late(56w) - Male 16.4 15.14 4.35 2.51 3

ANOVA result
Signif. codes ***: <0.001
**: <0.010
*: <0.050
†: <0.100
Factor df Sum Sq. F value Pr(>F) Signif.
condition1 1 454.61 33.0811 0.0004282 ***
sex 1 112.24 8.1676 0.0212198 *
condition1:sex 1 2.41 0.1755 0.6862742
Residuals 8 109.94

Tukey multiple comparisons of means
Factor: condition1
Level Difference Lower Upper Adjusted p
Late(56w) - Early(16w) -12.3 -17.2 -7.37 0.000428

Factor: sex
Level Difference Lower Upper Adjusted p
Male - Female -6.12 -11.1 -1.18 0.0212



FM_02_U_barchart.png

comment
CD11b+ Ly6C- NK was significantly decreased in 56-week-old mice (Late) relative to 16-week-old mice (Early) (p<0.001).