Procedure Grip Strength
Pipeline IMPC_adult_v2-LaterOnset Screen Age (week) 9-49w
Parameter Forelimb and hindlimb grip strength measurement mean
Strain Condition 1 Pipeline(s) Tested Day
(Age)
IMPC_adult_v2-LaterOnset
C57BL/6NJcl Late ♀: 11  ♂: 9 2015/10/06 - 2016/07/12
(9.36 - 49.93)
Early ♀: 14  ♂: 13
Raw Data

Bartlett test result
Factor df Bartlett's K2 p
condition1 1 5.819503e-05 0.9939133
sex 1 0.1880649 0.6645321

Summary statistics
Factor mean median SD SEM N
condition1 - sex
Early(9w) - Female 148.03 152.02 20.62 5.51 14
Early(9w) - Male 152.47 146.07 27.38 7.59 13
Late(49w) - Female 191.63 187.73 29.96 9.03 11
Late(49w) - Male 192.1 186.9 14.57 4.86 9

ANOVA result
Signif. codes ***: <0.001
**: <0.010
*: <0.050
†: <0.100
Factor df Sum Sq. F value Pr(>F) Signif.
condition1 1 20019.7 34.1545 6.159e-07 ***
sex 1 88.9 0.1517 0.6988
condition1:sex 1 44.9 0.0767 0.7832
Residuals 43 25204.5

Tukey multiple comparisons of means
Factor: condition1
Level Difference Lower Upper Adjusted p
Late(49w) - Early(9w) 41.7 27.3 56.1 6.35e-07



FM_02_U_barchart.png

comment
Forelimb and hindlimb grip strength measurement mean was significantly increased in 49-week-old mice (Late) relative to 9-week-old mice (Early) (p<0.01).