| Procedure | Grip Strength | ||
|---|---|---|---|
| Pipeline | IMPC_adult_v2-LaterOnset | Screen Age (week) | 9-49w |
| Parameter | Forelimb and hindlimb grip strength measurement maximum value | ||
| Strain | Condition 1 | Pipeline(s) | Tested Day (Age) |
|---|---|---|---|
| IMPC_adult_v2-LaterOnset | |||
| C57BL/6NJcl | Late | ♀: 11 ♂: 9 |
2015/10/06 - 2016/07/12 (9.36 - 49.93) |
| Early | ♀: 14 ♂: 13 |
| Factor | df | Bartlett's K2 | p |
|---|---|---|---|
| condition1 | 1 | 0.01101923 | 0.9163976 |
| sex | 1 | 0.01631340 | 0.8983674 |
| Factor | mean | median | SD | SEM | N |
|---|---|---|---|---|---|
| condition1 - sex | |||||
| Early(9w) - Female | 164.58 | 170 | 23.35 | 6.24 | 14 |
| Early(9w) - Male | 185.19 | 164.5 | 45.85 | 12.72 | 13 |
| Late(49w) - Female | 220.52 | 210.4 | 44.15 | 13.31 | 11 |
| Late(49w) - Male | 223.32 | 237.1 | 25.09 | 8.36 | 9 |
| Signif. codes ***: <0.001 **: <0.010 *: <0.050 †: <0.100 |
||||||
| Factor | df | Sum Sq. | F value | Pr(>F) | Signif. | |
|---|---|---|---|---|---|---|
| condition1 | 1 | 26103 | 19.7480 | 6.108e-05 | *** | |
| sex | 1 | 1998 | 1.5115 | 0.2256 | ||
| condition1:sex | 1 | 905 | 0.6849 | 0.4125 | ||
| Residuals | 43 | 56837 | ||||
| Level | Difference | Lower | Upper | Adjusted p |
|---|---|---|---|---|
| Late(49w) - Early(9w) | 47.3 | 25.6 | 68.9 | 6.85e-05 |
| comment |
|---|
| Forelimb and hindlimb grip strength measurement maximum value was significantly increased in 49-week-old mice (Late) relative to 9-week-old mice (Early) (p<0.01). |