Procedure Grip Strength
Pipeline IMPC_adult_v2-LaterOnset Screen Age (week) 9-49w
Parameter Forelimb and hindlimb grip strength measurement
Strain Condition 1 Pipeline(s) Tested Day
(Age)
IMPC_adult_v2-LaterOnset
C57BL/6NJcl Late ♀: 11  ♂: 9 2015/10/06 - 2016/07/12
(9.36 - 49.93)
Early ♀: 14  ♂: 13
Raw Data

Bartlett test result
Factor df Bartlett's K2 p
condition1 1 0.464067 0.4957294
sex 1 0.3941239 0.5301397

Summary statistics
Factor mean median SD SEM N
condition1 - sex
Early(9w) - Female 148.03 153.2 25.38 3.92 42
Early(9w) - Male 152.47 150 40.34 6.46 39
Late(49w) - Female 191.63 183.4 39.54 6.88 33
Late(49w) - Male 192.1 186.8 32.28 6.21 27

ANOVA result
Signif. codes ***: <0.001
**: <0.010
*: <0.050
†: <0.100
Factor df Sum Sq. F value Pr(>F) Signif.
condition1 1 60059 49.7558 7.85e-11 ***
sex 1 267 0.2210 0.6390
condition1:sex 1 135 0.1117 0.7387
Residuals 137 165370

Tukey multiple comparisons of means
Factor: condition1
Level Difference Lower Upper Adjusted p
Late(49w) - Early(9w) 41.7 30 53.4 8.33e-11



FM_02_U_barchart.png

comment
Forelimb and hindlimb grip strength measurement was significantly increased in 49-week-old mice (Late) relative to 9-week-old mice (Early) (p<0.01).