Genotype Viewer

Procedure	Eye Morphology v1.0
Pipeline	IMPC_adult_v2-LaterOnset	Screen Age (week)	15-53w
Parameter	Retinal Pigmentation

Strain	Condition 1	Pipeline(s)	Tested Day (Age)
Strain	Condition 1	IMPC_adult_v2-LaterOnset	Tested Day (Age)
C57BL/6NJcl	Late	♀: 9 ♂: 7	2015/11/17 - 2016/08/10 (15.5 - 53.79)
C57BL/6NJcl	Early	♀: 14 ♂: 13	2015/11/17 - 2016/08/10 (15.5 - 53.79)

Raw Data

Conditions of statistics.

sex	Female

Pearson's chi-square test
Chi-square	df	p
7.5322	1	0.006061

Observed value
		Retinal Pigmentation
		0	1
condition1	Early(15w)	14.0	0.0
condition1	Late(53w)	5.0	4.0

Expected value
		Retinal Pigmentation
		0	1
condition1	Early(15w)	11.565217	2.434783
condition1	Late(53w)	7.434783	1.565217

Standarized residuals
		Retinal Pigmentation
		0	1
condition1	Early(15w)	0.715951	-1.560379
condition1	Late(53w)	-0.8929478	1.946135

Adjusted residuals
		Retinal Pigmentation
		0	1
condition1	Early(15w)	2.744479	-2.744479
condition1	Late(53w)	-2.744479	2.744479

p of adjustment residual analysis
		Retinal Pigmentation
		0	1
condition1	Early(15w)	0.996969646	0.003030354
condition1	Late(53w)	0.003030354	0.996969646

Conditions of statistics.

sex	Male

Pearson's chi-square test
Chi-square	df	p
4.127	1	0.04220

Observed value
		Retinal Pigmentation
		0	1
condition1	Early(15w)	13.0	0.0
condition1	Late(53w)	5.0	2.0

Expected value
		Retinal Pigmentation
		0	1
condition1	Early(15w)	11.7	1.3
condition1	Late(53w)	6.3	0.7

Standarized residuals
		Retinal Pigmentation
		0	1
condition1	Early(15w)	0.3800585	-1.140175
condition1	Late(53w)	-0.5179324	1.553797

Adjusted residuals
		Retinal Pigmentation
		0	1
condition1	Early(15w)	2.031498	-2.031498
condition1	Late(53w)	-2.031498	2.031498

p of adjustment residual analysis
		Retinal Pigmentation
		0	1
condition1	Early(15w)	0.97889775	0.02110225
condition1	Late(53w)	0.02110225	0.97889775


	0 = normal		1 = left eye abnormal
	2 = right eye abnormal		3 = both eyes abnormal
	4 = no data left eye		5 = no data right eye
	6 = no data for both eyes
	7 = no data left eye, right eye abnormal
	8 = no data right eye, left eye abnormal


	0 = normal		1 = left eye abnormal
	2 = right eye abnormal		3 = both eyes abnormal
	4 = no data left eye		5 = no data right eye
	6 = no data for both eyes
	7 = no data left eye, right eye abnormal
	8 = no data right eye, left eye abnormal

comment
Some of 53 weeks old mice(Late) showed white spots of the retina getting larger and more than 15 weeks old mice(Early).