Procedure | Body Composition (DEXA lean/fat) v1 | ||
---|---|---|---|
Pipeline | IMPC_adult_v2-LaterOnset | Screen Age (week) | 14-54w |
Parameter | Bone Area (BMC/BMD) |
Strain | Condition 1 | Pipeline(s) | Tested Day (Age) |
---|---|---|---|
IMPC_adult_v2-LaterOnset | |||
C57BL/6NJcl | Late | ♀: 11 ♂: 9 |
2015/11/11 - 2016/08/15 (14.5 - 54.79) |
Early | ♀: 14 ♂: 13 |
Factor | df | Bartlett's K2 | p |
---|---|---|---|
condition1 | 1 | 2.524313 | 0.1121036 |
sex | 1 | 2.076457 | 0.1495870 |
Factor | mean | median | SD | SEM | N |
---|---|---|---|---|---|
condition1 - sex | |||||
Early(14w) - Female | 11.69 | 11.6 | 0.4 | 0.11 | 14 |
Early(14w) - Male | 11.06 | 11.39 | 0.67 | 0.18 | 13 |
Late(54w) - Female | 10.88 | 10.92 | 1.1 | 0.33 | 11 |
Late(54w) - Male | 10.64 | 10.9 | 0.53 | 0.18 | 9 |
Signif. codes ***: <0.001 **: <0.010 *: <0.050 : <0.100 |
||||||
Factor | df | Sum Sq. | F value | Pr(>F) | Signif. | |
---|---|---|---|---|---|---|
condition1 | 1 | 4.5810 | 9.0567 | 0.004365 | ** | |
sex | 1 | 2.5199 | 4.9820 | 0.030875 | * | |
condition1:sex | 1 | 0.4361 | 0.8622 | 0.358314 | ||
Residuals | 43 | 21.7499 | ||||
Level | Difference | Lower | Upper | Adjusted p |
---|---|---|---|---|
Late(54w) - Early(14w) | -0.617 | -1.04 | -0.194 | 0.00525 |
Level | Difference | Lower | Upper | Adjusted p |
---|---|---|---|---|
Male - Female | -0.464 | -0.883 | -0.0445 | 0.0310 |
comment |
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Bone Area was significantly decreased in 54-week-old mice (Late) relative to 14-week-old mice (Early) (p<0.01). |