Procedure Body Composition (DEXA lean/fat) v1
Pipeline IMPC_adult_v2-LaterOnset Screen Age (week) 14-54w
Parameter Bone Area (BMC/BMD)
Strain Condition 1 Pipeline(s) Tested Day
(Age)
IMPC_adult_v2-LaterOnset
C57BL/6NJcl Late ♀: 11  ♂: 9 2015/11/11 - 2016/08/15
(14.5 - 54.79)
Early ♀: 14  ♂: 13
Raw Data

Bartlett test result
Factor df Bartlett's K2 p
condition1 1 2.524313 0.1121036
sex 1 2.076457 0.1495870

Summary statistics
Factor mean median SD SEM N
condition1 - sex
Early(14w) - Female 11.69 11.6 0.4 0.11 14
Early(14w) - Male 11.06 11.39 0.67 0.18 13
Late(54w) - Female 10.88 10.92 1.1 0.33 11
Late(54w) - Male 10.64 10.9 0.53 0.18 9

ANOVA result
Signif. codes ***: <0.001
**: <0.010
*: <0.050
†: <0.100
Factor df Sum Sq. F value Pr(>F) Signif.
condition1 1 4.5810 9.0567 0.004365 **
sex 1 2.5199 4.9820 0.030875 *
condition1:sex 1 0.4361 0.8622 0.358314
Residuals 43 21.7499

Tukey multiple comparisons of means
Factor: condition1
Level Difference Lower Upper Adjusted p
Late(54w) - Early(14w) -0.617 -1.04 -0.194 0.00525

Factor: sex
Level Difference Lower Upper Adjusted p
Male - Female -0.464 -0.883 -0.0445 0.0310



FM_02_U_barchart.png

comment
Bone Area was significantly decreased in 54-week-old mice (Late) relative to 14-week-old mice (Early) (p<0.01).