Procedure Body Composition (DEXA lean/fat) v1
Pipeline IMPC_adult_v2-LaterOnset Screen Age (week) 14-54w
Parameter Body weight
Strain Condition 1 Pipeline(s) Tested Day
(Age)
IMPC_adult_v2-LaterOnset
C57BL/6NJcl Late ♀: 11  ♂: 9 2015/11/11 - 2016/08/15
(14.5 - 54.79)
Early ♀: 14  ♂: 13
Raw Data

Bartlett test result
Factor df Bartlett's K2 p
condition1 1 13.11439 0.0002930359
sex 1 0.8222301 0.3645289

Summary statistics
Factor mean median SD SEM N
condition1 - sex
Early(14w) - Female 25.21 24.8 1.89 0.51 14
Early(14w) - Male 31.05 31.6 2.69 0.74 13
Late(54w) - Female 36.09 33.1 7.08 2.13 11
Late(54w) - Male 47.18 49.4 4.68 1.56 9

ANOVA result
Signif. codes ***: <0.001
**: <0.010
*: <0.050
†: <0.100
Factor df Sum Sq. F value Pr(>F) Signif.
condition1 1 2035.04 108.0960 2.613e-13 ***
sex 1 759.66 40.3515 1.123e-07 ***
condition1:sex 1 78.60 4.1752 0.04718 *
Residuals 43 809.53

Tukey multiple comparisons of means
Factor: condition1
Level Difference Lower Upper Adjusted p
Late(54w) - Early(14w) 13.1 10.5 15.6 1.59e-12

Factor: sex
Level Difference Lower Upper Adjusted p
Male - Female 8.05 5.5 10.6 1.13e-07

Factor: condition1:sex
Level Difference Lower Upper Adjusted p
Late(54w):Female - Early(14w):Female 10.88 6.21 15.556 1.01e-06
Early(14w):Male - Early(14w):Female 5.84 1.37 10.305 5.92e-03
Late(54w):Male - Early(14w):Female 21.97 17.02 26.925 1.14e-12
Early(14w):Male - Late(54w):Female -5.04 -9.80 -0.294 3.36e-02
Late(54w):Male - Late(54w):Female 11.09 5.88 16.299 6.13e-06
Late(54w):Male - Early(14w):Male 16.13 11.10 21.160 4.43e-10



FM_02_U_barchart.png

comment
Body weight was significantly increased in 54-week-old mice (Late) relative to 14-week-old mice (Early)(p<0.001).