| Procedure | Body Composition (DEXA lean/fat) v1 | ||
|---|---|---|---|
| Pipeline | IMPC_adult_v2-LaterOnset | Screen Age (week) | 14-54w |
| Parameter | Bone Mineral Density (excluding skull) | ||
| Strain | Condition 1 | Pipeline(s) | Tested Day (Age) |
|---|---|---|---|
| IMPC_adult_v2-LaterOnset | |||
| C57BL/6NJcl | Late | ♀: 11 ♂: 9 |
2015/11/11 - 2016/08/15 (14.5 - 54.79) |
| Early | ♀: 14 ♂: 13 |
| Factor | df | Bartlett's K2 | p |
|---|---|---|---|
| condition1 | 1 | 3.993727 | 0.04566993 |
| sex | 1 | 4.296969 | 0.03818036 |
| Factor | mean | median | SD | SEM | N |
|---|---|---|---|---|---|
| condition1 - sex | |||||
| Early(14w) - Female | 0.05 | 0.05 | 0 | 0 | 14 |
| Early(14w) - Male | 0.05 | 0.05 | 0 | 0 | 13 |
| Late(54w) - Female | 0.05 | 0.05 | 0 | 0 | 11 |
| Late(54w) - Male | 0.05 | 0.05 | 0 | 0 | 9 |
| Signif. codes ***: <0.001 **: <0.010 *: <0.050 †: <0.100 |
||||||
| Factor | df | Sum Sq. | F value | Pr(>F) | Signif. | |
|---|---|---|---|---|---|---|
| condition1 | 1 | 1.8604e-04 | 61.3221 | 8.241e-10 | *** | |
| sex | 1 | 8.8558e-05 | 29.1903 | 2.681e-06 | *** | |
| condition1:sex | 1 | 8.9570e-06 | 2.9524 | 0.09294 | † | |
| Residuals | 43 | 1.3045e-04 | ||||
| Level | Difference | Lower | Upper | Adjusted p |
|---|---|---|---|---|
| Late(54w) - Early(14w) | 0.00411 | 0.00308 | 0.00515 | 4.7e-10 |
| Level | Difference | Lower | Upper | Adjusted p |
|---|---|---|---|---|
| Male - Female | -0.00275 | -0.00378 | -0.00172 | 2.70e-06 |
| comment |
|---|
| Bone Mineral Density was significantly increased in 54-week-old mice (Late) relative to 14-week-old mice (Early)(p<0.001). |