Procedure Combined SHIRPA and Dysmorphology v1.1
Pipeline IMPC_adult_v2-LaterOnset Screen Age (week) 9-49w
Parameter Group Body size
Parameter Body weight
Strain Condition 1 Pipeline(s) Tested Day
(Age)
IMPC_adult_v2-LaterOnset
C57BL/6NJcl Late ♀: 11  ♂: 9 2015/10/06 - 2016/07/12
(9.36 - 49.93)
Early ♀: 14  ♂: 13
Raw Data

Bartlett test result
Factor df Bartlett's K2 p
condition1 1 24.74737 6.535789e-07
sex 1 1.247820 0.2639693

Summary statistics
Factor mean median SD SEM N
condition1 - sex
Early(9w) - Female 22.59 22.1 1.33 0.35 14
Early(9w) - Male 27.58 28 1.87 0.52 13
Late(49w) - Female 36.42 32.8 8.02 2.42 11
Late(49w) - Male 48.68 51.2 4.92 1.64 9

ANOVA result
Signif. codes ***: <0.001
**: <0.010
*: <0.050
†: <0.100
Factor df Sum Sq. F value Pr(>F) Signif.
condition1 1 3394.3 161.6990 3.331e-16 ***
sex 1 762.0 36.2978 3.365e-07 ***
condition1:sex 1 150.5 7.1677 0.01047 *
Residuals 43 902.6

Tukey multiple comparisons of means
Factor: condition1
Level Difference Lower Upper Adjusted p
Late(49w) - Early(9w) 16.9 14.2 19.7 1.11e-12

Factor: sex
Level Difference Lower Upper Adjusted p
Male - Female 8.07 5.36 10.8 3.4e-07

Factor: condition1:sex
Level Difference Lower Upper Adjusted p
Late(49w):Female - Early(9w):Female 13.83 8.899 18.77 1.49e-08
Early(9w):Male - Early(9w):Female 5.00 0.283 9.71 3.40e-02
Late(49w):Male - Early(9w):Female 26.09 20.861 31.32 1.11e-12
Early(9w):Male - Late(49w):Female -8.83 -13.850 -3.82 1.50e-04
Late(49w):Male - Late(49w):Female 12.26 6.756 17.76 2.51e-06
Late(49w):Male - Early(9w):Male 21.09 15.784 26.40 1.94e-12



FM_02_U_barchart.png

comment
Body weight was significantly increased in 49-week-old mice (Late) relative to 9-week-old mice (Early) in both sexes (p<0.01).