| Procedure | Clinical Blood Chemistry Clinical biochemical test v2 | ||
|---|---|---|---|
| Pipeline | IMPC_adult_v2-LaterOnset | Screen Age (week) | 16-56w |
| Parameter | Total bilirubin (T-BIL) | ||
| Strain | Condition 1 | Pipeline(s) | Tested Day (Age) |
|---|---|---|---|
| IMPC_adult_v2-LaterOnset | |||
| C57BL/6NJcl | Late | ♀: 11 ♂: 8 |
2015/11/25 - 2016/08/31 (16.5 - 56.93) |
| Early | ♀: 14 ♂: 12 |
| Factor | df | Bartlett's K2 | p |
|---|---|---|---|
| condition1 | 1 | 9.387084 | 0.002185196 |
| sex | 1 | 3.099012 | 0.07833984 |
| Factor | mean | median | SD | SEM | N |
|---|---|---|---|---|---|
| condition1 - sex | |||||
| Early(16w) - Female | 0.05 | 0.05 | 0.02 | 0 | 14 |
| Early(16w) - Male | 0.04 | 0.03 | 0.04 | 0.01 | 12 |
| Late(56w) - Female | 0.01 | 0 | 0.01 | 0 | 11 |
| Late(56w) - Male | 0.02 | 0.01 | 0.01 | 0 | 8 |
| Signif. codes ***: <0.001 **: <0.010 *: <0.050 †: <0.100 |
||||||
| Factor | df | Sum Sq. | F value | Pr(>F) | Signif. | |
|---|---|---|---|---|---|---|
| condition1 | 1 | 0.0112538 | 18.9917 | 8.594e-05 | *** | |
| sex | 1 | 0.0000452 | 0.0763 | 0.7838 | ||
| condition1:sex | 1 | 0.0002101 | 0.3546 | 0.5548 | ||
| Residuals | 41 | 0.0242951 | ||||
| Level | Difference | Lower | Upper | Adjusted p |
|---|---|---|---|---|
| Late(56w) - Early(16w) | -0.0321 | -0.047 | -0.0173 | 8.21e-05 |
| comment |
|---|
| T-BIL was significantly decreased in 56-week-old mice (Late) relative to 16-week-old mice (Early) (p<0.001). |