Procedure | Hematology Blood collection for hematological test v2 | ||
---|---|---|---|
Pipeline | IMPC_adult_v2-LaterOnset | Screen Age (week) | 16-56w |
Parameter | Absolute number of neutrophils (NEUT number) |
Strain | Condition 1 | Pipeline(s) | Tested Day (Age) |
---|---|---|---|
IMPC_adult_v2-LaterOnset | |||
C57BL/6NJcl | Late | ♀: 10 ♂: 8 |
2015/11/24 - 2016/08/29 (16.36 - 56.64) |
Early | ♀: 14 ♂: 11 |
Factor | df | Bartlett's K2 | p |
---|---|---|---|
condition1 | 1 | 1.472004 | 0.2250298 |
sex | 1 | 5.162988 | 0.02307317 |
Factor | mean | median | SD | SEM | N |
---|---|---|---|---|---|
condition1 - sex | |||||
Early(16w) - Female | 0.83 | 0.8 | 0.18 | 0.05 | 14 |
Early(16w) - Male | 0.71 | 0.7 | 0.14 | 0.04 | 11 |
Late(56w) - Female | 0.55 | 0.48 | 0.25 | 0.08 | 10 |
Late(56w) - Male | 0.67 | 0.71 | 0.17 | 0.06 | 8 |
Signif. codes ***: <0.001 **: <0.010 *: <0.050 : <0.100 |
||||||
Factor | df | Sum Sq. | F value | Pr(>F) | Signif. | |
---|---|---|---|---|---|---|
condition1 | 1 | 0.31958 | 9.0882 | 0.004507 | ** | |
sex | 1 | 0.00259 | 0.0737 | 0.787402 | ||
condition1:sex | 1 | 0.15241 | 4.3341 | 0.043965 | * | |
Residuals | 39 | 1.37142 | ||||
Level | Difference | Lower | Upper | Adjusted p |
---|---|---|---|---|
Late(56w) - Early(16w) | -0.175 | -0.292 | -0.0576 | 0.00449 |
Level | Difference | Lower | Upper | Adjusted p |
---|---|---|---|---|
Late(56w):Female - Early(16w):Female | -0.2823 | -0.491 | -0.0739 | 0.00427 |
Early(16w):Male - Early(16w):Female | -0.1175 | -0.320 | 0.0853 | 0.41575 |
Late(56w):Male - Early(16w):Female | -0.1568 | -0.380 | 0.0662 | 0.25038 |
Early(16w):Male - Late(56w):Female | 0.1648 | -0.055 | 0.3847 | 0.20126 |
Late(56w):Male - Late(56w):Female | 0.1255 | -0.113 | 0.3642 | 0.50031 |
Late(56w):Male - Early(16w):Male | -0.0393 | -0.273 | 0.1945 | 0.96900 |
comment |
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NEUT number was significantly decreased in 56-week-old mice (Late) relative to 16-week-old mice (Early) in only female (p<0.01). |