Procedure | Hematology Blood collection for hematological test v2 | ||
---|---|---|---|
Pipeline | IMPC_adult_v2-LaterOnset | Screen Age (week) | 16-56w |
Parameter | Absolute number of lymphocytes (LYMP number) |
Strain | Condition 1 | Pipeline(s) | Tested Day (Age) |
---|---|---|---|
IMPC_adult_v2-LaterOnset | |||
C57BL/6NJcl | Late | ♀: 10 ♂: 8 |
2015/11/24 - 2016/08/29 (16.36 - 56.64) |
Early | ♀: 14 ♂: 11 |
Factor | df | Bartlett's K2 | p |
---|---|---|---|
condition1 | 1 | 9.289393 | 0.002304845 |
sex | 1 | 2.693419 | 0.1007634 |
Factor | mean | median | SD | SEM | N |
---|---|---|---|---|---|
condition1 - sex | |||||
Early(16w) - Female | 5.01 | 5.12 | 1.05 | 0.28 | 14 |
Early(16w) - Male | 5.64 | 5.58 | 1.5 | 0.45 | 11 |
Late(56w) - Female | 2.98 | 2.79 | 1.04 | 0.33 | 10 |
Late(56w) - Male | 6.22 | 6.94 | 2.79 | 0.99 | 8 |
Signif. codes ***: <0.001 **: <0.010 *: <0.050 : <0.100 |
||||||
Factor | df | Sum Sq. | F value | Pr(>F) | Signif. | |
---|---|---|---|---|---|---|
condition1 | 1 | 8.033 | 3.0958 | 0.086340 | | |
sex | 1 | 31.289 | 12.0586 | 0.001276 | ** | |
condition1:sex | 1 | 17.579 | 6.7748 | 0.013007 | * | |
Residuals | 39 | 101.196 | ||||
Level | Difference | Lower | Upper | Adjusted p |
---|---|---|---|---|
Male - Female | 1.72 | 0.717 | 2.72 | 0.00128 |
Level | Difference | Lower | Upper | Adjusted p |
---|---|---|---|---|
Late(56w):Female - Early(16w):Female | -2.031 | -3.821 | -0.241 | 0.020759 |
Early(16w):Male - Early(16w):Female | 0.624 | -1.117 | 2.366 | 0.771798 |
Late(56w):Male - Early(16w):Female | 1.202 | -0.713 | 3.118 | 0.345461 |
Early(16w):Male - Late(56w):Female | 2.655 | 0.766 | 4.544 | 0.002903 |
Late(56w):Male - Late(56w):Female | 3.234 | 1.183 | 5.284 | 0.000757 |
Late(56w):Male - Early(16w):Male | 0.578 | -1.430 | 2.587 | 0.866246 |
comment |
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LYMP number was significantly decreased in 56-week-old mice (Late) relative to 16-week-old mice (Early) in only female (p<0.05). |