| Procedure | Hematology Blood collection for hematological test v2 | ||
|---|---|---|---|
| Pipeline | IMPC_adult_v2-LaterOnset | Screen Age (week) | 16-56w |
| Parameter | Absolute number of Large Unstained Cells (LUC number) | ||
| Strain | Condition 1 | Pipeline(s) | Tested Day (Age) |
|---|---|---|---|
| IMPC_adult_v2-LaterOnset | |||
| C57BL/6NJcl | Late | ♀: 10 ♂: 8 |
2015/11/24 - 2016/08/29 (16.36 - 56.64) |
| Early | ♀: 14 ♂: 11 |
| Factor | df | Bartlett's K2 | p |
|---|---|---|---|
| condition1 | 1 | 17.45055 | 2.948784e-05 |
| sex | 1 | 5.205567 | 0.02251467 |
| Factor | mean | median | SD | SEM | N |
|---|---|---|---|---|---|
| condition1 - sex | |||||
| Early(16w) - Female | 0.04 | 0.04 | 0.01 | 0 | 14 |
| Early(16w) - Male | 0.04 | 0.05 | 0.02 | 0.01 | 11 |
| Late(56w) - Female | 0.04 | 0.03 | 0.03 | 0.01 | 10 |
| Late(56w) - Male | 0.07 | 0.07 | 0.04 | 0.02 | 8 |
| Signif. codes ***: <0.001 **: <0.010 *: <0.050 †: <0.100 |
||||||
| Factor | df | Sum Sq. | F value | Pr(>F) | Signif. | |
|---|---|---|---|---|---|---|
| condition1 | 1 | 0.0022945 | 3.0400 | 0.08912 | † | |
| sex | 1 | 0.0018979 | 2.5145 | 0.12088 | ||
| condition1:sex | 1 | 0.0036602 | 4.8494 | 0.03364 | * | |
| Residuals | 39 | 0.0294359 | ||||
| Level | Difference | Lower | Upper | Adjusted p |
|---|---|---|---|---|
| Late(56w):Female - Early(16w):Female | -0.001857 | -0.032380 | 0.0287 | 0.9984 |
| Early(16w):Male - Early(16w):Female | -0.002403 | -0.032105 | 0.0273 | 0.9963 |
| Late(56w):Male - Early(16w):Female | 0.033393 | 0.000720 | 0.0661 | 0.0435 |
| Early(16w):Male - Late(56w):Female | -0.000545 | -0.032756 | 0.0317 | 1.0000 |
| Late(56w):Male - Late(56w):Female | 0.035250 | 0.000281 | 0.0702 | 0.0476 |
| Late(56w):Male - Early(16w):Male | 0.035795 | 0.001541 | 0.0701 | 0.0376 |
| comment |
|---|
| LUC number was significantly increased in 56-week-old mice (Late) relative to 16-week-old mice (Early) in only female (p<0.05). |