| Procedure | Hematology Blood collection for hematological test v2 | ||
|---|---|---|---|
| Pipeline | IMPC_adult_v2-LaterOnset | Screen Age (week) | 16-56w |
| Parameter | Mean platelet volume (MPV) | ||
| Strain | Condition 1 | Pipeline(s) | Tested Day (Age) |
|---|---|---|---|
| IMPC_adult_v2-LaterOnset | |||
| C57BL/6NJcl | Late | ♀: 10 ♂: 8 |
2015/11/24 - 2016/08/29 (16.36 - 56.64) |
| Early | ♀: 14 ♂: 11 |
| Factor | df | Bartlett's K2 | p |
|---|---|---|---|
| condition1 | 1 | 0.2374639 | 0.6260439 |
| sex | 1 | 0.4109025 | 0.5215118 |
| Factor | mean | median | SD | SEM | N |
|---|---|---|---|---|---|
| condition1 - sex | |||||
| Early(16w) - Female | 6.68 | 6.7 | 0.17 | 0.04 | 14 |
| Early(16w) - Male | 6.57 | 6.6 | 0.34 | 0.1 | 11 |
| Late(56w) - Female | 6.1 | 6.05 | 0.27 | 0.09 | 10 |
| Late(56w) - Male | 6.06 | 5.9 | 0.32 | 0.11 | 8 |
| Signif. codes ***: <0.001 **: <0.010 *: <0.050 †: <0.100 |
||||||
| Factor | df | Sum Sq. | F value | Pr(>F) | Signif. | |
|---|---|---|---|---|---|---|
| condition1 | 1 | 3.14637 | 41.3976 | 1.294e-07 | *** | |
| sex | 1 | 0.06320 | 0.8316 | 0.3674 | ||
| condition1:sex | 1 | 0.01206 | 0.1587 | 0.6926 | ||
| Residuals | 39 | 2.96414 | ||||
| Level | Difference | Lower | Upper | Adjusted p |
|---|---|---|---|---|
| Late(56w) - Early(16w) | -0.549 | -0.721 | -0.376 | 1.28e-07 |
| comment |
|---|
| MPV was significantly decreased in 56-week-old mice (Late) relative to 16-week-old mice (Early) (p<0.01). |