Procedure Hematology Blood collection for hematological test v2
Pipeline IMPC_adult_v2-LaterOnset Screen Age (week) 16-56w
Parameter Mean corpuscular hemoglobin (MCH)
Strain Condition 1 Pipeline(s) Tested Day
(Age)
IMPC_adult_v2-LaterOnset
C57BL/6NJcl Late ♀: 10  ♂: 8 2015/11/24 - 2016/08/29
(16.36 - 56.64)
Early ♀: 14  ♂: 11
Raw Data

Bartlett test result
Factor df Bartlett's K2 p
condition1 1 6.503179 0.01076818
sex 1 0.004810203 0.9447065

Summary statistics
Factor mean median SD SEM N
condition1 - sex
Early(16w) - Female 15.12 15.15 0.26 0.07 14
Early(16w) - Male 14.91 15 0.18 0.05 11
Late(56w) - Female 14.88 14.85 0.43 0.13 10
Late(56w) - Male 14.56 14.55 0.43 0.15 8

ANOVA result
Signif. codes ***: <0.001
**: <0.010
*: <0.050
†: <0.100
Factor df Sum Sq. F value Pr(>F) Signif.
condition1 1 0.8678 8.1214 0.006953 **
sex 1 0.6972 6.5248 0.014657 *
condition1:sex 1 0.0286 0.2672 0.608139
Residuals 39 4.1674

Tukey multiple comparisons of means
Factor: condition1
Level Difference Lower Upper Adjusted p
Late(56w) - Early(16w) -0.289 -0.494 -0.0847 0.00675

Factor: sex
Level Difference Lower Upper Adjusted p
Male - Female -0.256 -0.459 -0.0534 0.0147



FM_02_U_barchart.png

comment
MCH was significantly decreased in 56-week-old mice (Late) relative to 16-week-old mice (Early) (p<0.01).