Procedure Hematology Blood collection for hematological test v2
Pipeline IMPC_adult_v2-LaterOnset Screen Age (week) 16-56w
Parameter Hemoglobin (HGB)
Strain Condition 1 Pipeline(s) Tested Day
(Age)
IMPC_adult_v2-LaterOnset
C57BL/6NJcl Late ♀: 10  ♂: 8 2015/11/24 - 2016/08/29
(16.36 - 56.64)
Early ♀: 14  ♂: 11
Raw Data

Bartlett test result
Factor df Bartlett's K2 p
condition1 1 0.002173567 0.9628149
sex 1 0.7775229 0.3778998

Summary statistics
Factor mean median SD SEM N
condition1 - sex
Early(16w) - Female 15.82 15.95 0.4 0.11 14
Early(16w) - Male 16.43 16.6 0.46 0.14 11
Late(56w) - Female 14.91 14.9 0.62 0.2 10
Late(56w) - Male 15.03 14.95 0.36 0.13 8

ANOVA result
Signif. codes ***: <0.001
**: <0.010
*: <0.050
†: <0.100
Factor df Sum Sq. F value Pr(>F) Signif.
condition1 1 13.3311 60.9557 1.714e-09 ***
sex 1 1.6978 7.7630 0.008193 **
condition1:sex 1 0.6220 2.8441 0.099695 †
Residuals 39 8.5294

Tukey multiple comparisons of means
Factor: condition1
Level Difference Lower Upper Adjusted p
Late(56w) - Early(16w) -1.13 -1.42 -0.834 1.78e-09

Factor: sex
Level Difference Lower Upper Adjusted p
Male - Female 0.4 0.110 0.69 0.0082



FM_02_U_barchart.png

comment
HGB was significantly decreased in 56-week-old mice (Late) relative to 16-week-old mice (Early) (p<0.01).