Procedure Hematology Blood collection for hematological test v2
Pipeline IMPC_adult_v2-LaterOnset Screen Age (week) 16-56w
Parameter Hematocrit (HCT)
Strain Condition 1 Pipeline(s) Tested Day
(Age)
IMPC_adult_v2-LaterOnset
C57BL/6NJcl Late ♀: 10  ♂: 8 2015/11/24 - 2016/08/29
(16.36 - 56.64)
Early ♀: 14  ♂: 11
Raw Data

Bartlett test result
Factor df Bartlett's K2 p
condition1 1 0.6201529 0.4309905
sex 1 0.5266766 0.4680075

Summary statistics
Factor mean median SD SEM N
condition1 - sex
Early(16w) - Female 53.14 54 1.69 0.45 14
Early(16w) - Male 55.53 55.9 1.84 0.55 11
Late(56w) - Female 49.48 49.6 1.79 0.57 10
Late(56w) - Male 50.75 50.6 1.54 0.54 8

ANOVA result
Signif. codes ***: <0.001
**: <0.010
*: <0.050
†: <0.100
Factor df Sum Sq. F value Pr(>F) Signif.
condition1 1 180.414 60.4221 1.906e-09 ***
sex 1 39.153 13.1128 0.0008342 ***
condition1:sex 1 3.248 1.0876 0.3034197
Residuals 39 116.450

Tukey multiple comparisons of means
Factor: condition1
Level Difference Lower Upper Adjusted p
Late(56w) - Early(16w) -4.14 -5.22 -3.06 2e-09

Factor: sex
Level Difference Lower Upper Adjusted p
Male - Female 1.92 0.848 2.99 0.000834



FM_02_U_barchart.png

comment
HCT was significantly decreased in 56-week-old mice (Late) relative to 16-week-old mice (Early) (p<0.01).