| Procedure | Pathology | ||
|---|---|---|---|
| Pipeline | IMPC_adult_v2-LaterOnset | Screen Age (week) | 16-56w |
| Parameter Group | Heart (weight) | ||
| Parameter | Heart weight | ||
| Strain | Condition 1 | Pipeline(s) | Tested Day (Age) |
|---|---|---|---|
| IMPC_adult_v2-LaterOnset | |||
| C57BL/6NJcl | Late | ♀: 11 ♂: 9 |
2015/11/26 - 2016/08/31 (17.07 - 56.93) |
| Early | ♀: 3 ♂: 3 |
| Factor | df | Bartlett's K2 | p |
|---|---|---|---|
| condition1 | 1 | 0.00373292 | 0.9512815 |
| sex | 1 | 0.2664620 | 0.605715 |
| Factor | mean | median | SD | SEM | N |
|---|---|---|---|---|---|
| condition1 - sex | |||||
| Early(16w) - Female | 118.6 | 113.3 | 12.99 | 7.5 | 3 |
| Early(16w) - Male | 151.3 | 154.7 | 14.99 | 8.66 | 3 |
| Late(56w) - Female | 141.07 | 137 | 14.31 | 4.31 | 11 |
| Late(56w) - Male | 172.16 | 175 | 18.28 | 6.09 | 9 |
| Signif. codes ***: <0.001 **: <0.010 *: <0.050 †: <0.100 |
||||||
| Factor | df | Sum Sq. | F value | Pr(>F) | Signif. | |
|---|---|---|---|---|---|---|
| condition1 | 1 | 2166.0 | 8.6499 | 0.007557 | ** | |
| sex | 1 | 6383.3 | 25.4913 | 4.681e-05 | *** | |
| condition1:sex | 1 | 3.0 | 0.0120 | 0.913683 | ||
| Residuals | 22 | 5509.1 | ||||
| Level | Difference | Lower | Upper | Adjusted p |
|---|---|---|---|---|
| Late(56w) - Early(16w) | 20.1 | 4.83 | 35.4 | 0.0122 |
| Level | Difference | Lower | Upper | Adjusted p |
|---|---|---|---|---|
| Male - Female | 31.4 | 18.5 | 44.3 | 4.73e-05 |
| comment |
|---|
| Heart weight was significantly increased in 56-week-old mice (Late) relative to 16-week-old mice (Early) (p<0.01). |