| Procedure | Acoustic startle and Pre-pulse Inhibition (PPI) v1 | ||
|---|---|---|---|
| Pipeline | IMPC_adult_v2-LaterOnset | Screen Age (week) | 10-50w |
| Parameter | Response amplitude - S | ||
| Strain | Condition 1 | Pipeline(s) | Tested Day (Age) |
|---|---|---|---|
| IMPC_adult_v2-LaterOnset | |||
| C57BL/6NJcl | Late | ♀: 11 ♂: 9 |
2015/10/13 - 2016/07/20 (10.36 - 51.07) |
| Early | ♀: 14 ♂: 13 |
| Factor | df | Bartlett's K2 | p |
|---|---|---|---|
| condition1 | 1 | 0.05607182 | 0.8128159 |
| sex | 1 | 4.160214 | 0.04138416 |
| Factor | mean | median | SD | SEM | N |
|---|---|---|---|---|---|
| condition1 - sex | |||||
| Early(10w) - Female | 1.45 | 1.29 | 0.42 | 0.11 | 14 |
| Early(10w) - Male | 1.91 | 1.99 | 0.62 | 0.17 | 13 |
| Late(50w) - Female | 0.73 | 0.86 | 0.36 | 0.11 | 11 |
| Late(50w) - Male | 0.88 | 0.63 | 0.72 | 0.24 | 9 |
| Signif. codes ***: <0.001 **: <0.010 *: <0.050 †: <0.100 |
||||||
| Factor | df | Sum Sq. | F value | Pr(>F) | Signif. | |
|---|---|---|---|---|---|---|
| condition1 | 1 | 8.4803 | 29.4683 | 2.462e-06 | *** | |
| sex | 1 | 1.2421 | 4.3161 | 0.04376 | * | |
| condition1:sex | 1 | 0.2704 | 0.9397 | 0.33776 | ||
| Residuals | 43 | 12.3743 | ||||
| Level | Difference | Lower | Upper | Adjusted p |
|---|---|---|---|---|
| Late(50w) - Early(10w) | -0.87 | -1.19 | -0.551 | 1.97e-06 |
| Level | Difference | Lower | Upper | Adjusted p |
|---|---|---|---|---|
| Male - Female | 0.326 | 0.00938 | 0.642 | 0.0439 |
| comment |
|---|
| Response amplitude - S was significantly decreased in 50-week-old mice (Late) relative to 10-week-old mice (Early) (p<.01). |