| Procedure | Acoustic startle and Pre-pulse Inhibition (PPI) v1 | ||
|---|---|---|---|
| Pipeline | IMPC_adult_v2-LaterOnset | Screen Age (week) | 10-50w |
| Parameter | Response amplitude - PP2 S | ||
| Strain | Condition 1 | Pipeline(s) | Tested Day (Age) |
|---|---|---|---|
| IMPC_adult_v2-LaterOnset | |||
| C57BL/6NJcl | Late | ♀: 11 ♂: 9 |
2015/10/13 - 2016/07/20 (10.36 - 51.07) |
| Early | ♀: 14 ♂: 13 |
| Factor | df | Bartlett's K2 | p |
|---|---|---|---|
| condition1 | 1 | 13.33796 | 0.0002600875 |
| sex | 1 | 2.822457 | 0.09295399 |
| Factor | mean | median | SD | SEM | N |
|---|---|---|---|---|---|
| condition1 - sex | |||||
| Early(10w) - Female | 0.59 | 0.52 | 0.29 | 0.08 | 14 |
| Early(10w) - Male | 0.73 | 0.59 | 0.43 | 0.12 | 13 |
| Late(50w) - Female | 0.23 | 0.16 | 0.17 | 0.05 | 11 |
| Late(50w) - Male | 0.17 | 0.15 | 0.13 | 0.04 | 9 |
| Signif. codes ***: <0.001 **: <0.010 *: <0.050 †: <0.100 |
||||||
| Factor | df | Sum Sq. | F value | Pr(>F) | Signif. | |
|---|---|---|---|---|---|---|
| condition1 | 1 | 2.3645 | 27.6145 | 4.375e-06 | *** | |
| sex | 1 | 0.0380 | 0.4442 | 0.5087 | ||
| condition1:sex | 1 | 0.1034 | 1.2075 | 0.2779 | ||
| Residuals | 43 | 3.6819 | ||||
| Level | Difference | Lower | Upper | Adjusted p |
|---|---|---|---|---|
| Late(50w) - Early(10w) | -0.456 | -0.63 | -0.282 | 4.05e-06 |
| comment |
|---|
| Response amplitude - PP2 S was significantly decreased in 50-week-old mice (Late) relative to 10-week-old mice (Early) (p<.01). |