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Toki H1, Inoue M, Minowa O, Motegi H, Saiki Y, Wakana S, Masuya H, Gondo Y, Shiroishi T, Yao R, Noda T.
Novel retinoblastoma mutation abrogating the interaction to E2F2/3, but not E2F1, led to selective suppression of thyroid tumors.
Cancer Sci. 2014 Oct;105(10):1360-8.


Toki H1, Inoue M, Motegi H, Minowa O, Kanda H, Yamamoto N, Ikeda A, Karashima Y, Matsui J, Kaneda H, Miura I, Suzuki T, Wakana S, Masuya H, Gondo Y, Shiroishi T, Akiyama T, Yao R, Noda T.
Novel mouse model for Gardner syndrome generated by a large-scale N-ethyl-N-nitrosourea mutagenesis program.
Cancer Sci. 2013 Jul;104(7):937-44.


Furuse T1, Yamada I, Kushida T, Masuya H, Miura I, Kaneda H, Kobayashi K, Wada Y, Yuasa S, Wakana S.
Behavioral and neuromorphological characterization of a novel Tuba1 mutant mouse.
Behav Brain Res. 2012 Feb 1;227(1):167-74.


Furuichi T, Masuya H, Murakami T, Nishida K, Nishimura G, Suzuki T, Imaizumi K, Kudo T, Ohkawa K, Wakana S, Ikegawa S.
ENU-induced missense mutation in the C-propeptide coding region of Col2a1 creates a mouse model of platyspondylic lethal skeletal dysplasia, Torrance type.
Mamm Genome. 2011 May 3. [Epub ahead of print]


Wada Y, Furuse T, Yamada I, Masuya H, Kushida T, Shibukawa Y, Nakai Y, Kobayashi K, Kaneda H, Gondo Y, Noda T, Shiroishi T, Wakana S.
ENU mutagenesis screening for dominant behavioral mutations based on normal control data obtained in home-cage activity, open-field, and passive avoidance tests.
Exp Anim. 2010;59(4):495-510.


Furuse T, Wada Y, Hattori K, Yamada I, Kushida T, Shibukawa Y, Masuya H, Kaneda H, Miura I, Seno N, Kanda T, Hirose R, Toki S, Nakanishi K, Kobayashi K, Sezutsu H, Gondo Y, Noda T, Yuasa S, Wakana S.
Phenotypic characterization of a new Grin1 mutant mouse generated by ENU mutagenesis.
Eur J Neurosci. 2010 31:1281-1291.



Sato H, Suzuki T, Ikeda K, Masuya H, Sezutsu H, Kaneda H, Kobayashi K, Miura I, Kurihara Y, Yokokura S, Nishida K, Tamai M, Gondo Y, Noda T, Wakana S.
A monogenic dominant mutation in Rom1 generated by N-ethyl-N-nitrosourea mutagenesis causes retinal degeneration in mice.
Mol Vis. 2010 16:378-391.



Wakana S, Suzuki T, Furuse T, Kobayashi K, Miura I, Kaneda H, Yamada I, Motegi H, Toki H, Inoue M, Minowa O, Noda T, Waki K, Tanaka N, Masuya H, Obata Y.
Introduction to the Japan Mouse Clinic at the RIKEN BioResource Center
Exp Anim. 2009 58:443-450.


Sakuraba Y, Kimura T, Masuya H, Noguchi H, Sezutsu H, Takahasi KR, Toyoda A, Fukumura R, Murata T, Sakaki Y, Yamamura M, Wakana S, Noda T, Shiroishi T, Gondo Y.
Identification and characterization of new long conserved noncoding sequences in vertebrates.
Mamm Genome. 2008 19:703-712.


Tanaka S, Miura I, Yoshiki A, Kato Y, Yokoyama H, Shinogi A, Masuya H, Wakana S, Tamura M, Shiroishi T.
Mutations in the helix termination motif of mouse type I IRS keratin genes impair the assembly of keratin intermediate filament.
Genomics. 2007 90:703-711.


Masuya H, Nishida K, Furuichi T, Toki H, Nishimura G, Kawabata H, Yokoyama H, Yoshida A, Tominaga S, Nagano J, Shimizu A, Wakana S, Gondo Y, Noda T, Shiroishi T, Ikegawa S.
A novel dominant-negative mutation in Gdf5 generated by ENU mutagenesis impairs joint formation and causes osteoarthritis in mice.
Hum Mol Genet. 2007 16:2366-2375.


Masuya H, Sezutsu H, Sakuraba Y, Sagai T, Hosoya M, Kaneda H, Miura I, Kobayashi K, Sumiyama K, Shimizu A, Nagano J, Yokoyama H, Kaneko S, Sakurai N, Okagaki Y, Noda T, Wakana S, Gondo Y, Shiroishi T.
A series of ENU-induced single-base substitutions in a long-range cis-element altering Sonic hedgehog expression in the developing mouse limb bud.
Genomics. 2007 89:207-214.


Masuya H, Shimizu K, Sezutsu H, Sakuraba Y, Nagano J, Shimizu A, Fujimoto N, Kawai A, Miura I, Kaneda H, Kobayashi K, Ishijima J, Maeda T, Gondo Y, Noda T, Wakana S, Shiroishi T.
Enamelin (Enam) is essential for amelogenesis: ENU-induced mouse mutants as models for different clinical subtypes of human amelogenesis imperfecta (AI), Hum Mol Genet. 2005 14:575-583.


Sakuraba Y, Sezutsu H, Takahasi KR, Tsuchihashi K, Ichikawa R, Fujimoto N, Kaneko S, Nakai Y, Uchiyama M, Goda N, Motoi R, Ikeda A, Karashima Y, Inoue M, Kaneda H, Masuya H, Minowa O, Noguchi H, Toyoda A, Sakaki Y, Wakana S, Noda T, Shiroishi T, Gondo Y.
Molecular characterization of ENU mouse mutagenesis and archives. Biochem Biophys Res Commun. 2005 336:609-616.


Masuya H, Inoue M, Wada Y, Shimizu A, Nagano J, Kawai A, Inoue A, Kagami T, Hirayama T, Yamaga A, Kaneda H, Kobayashi K, Minowa O, Miura I, Gondo Y, Noda T, Wakana S, Shiroishi T.
Implementation of the modified-SHIRPA protocol for screening of dominant phenotypes in a large-scale ENU mutagenesis program.
Mamm Genome. 2005 16:829-837.


Sagai T, Masuya H, Tamura M, Shimizu K, Yada Y, Wakana S, Gondo Y, Noda T, Shiroishi T.
Phylogenetic conservation of a limb-specific, cis-acting regulator of Sonic hedgehog ( Shh).
Mamm Genome. 2004 15:23-34.


Kikkawa Y, Oyama A, Ishii R, Miura I, Amano T, Ishii Y, Yoshikawa Y, Masuya H, Wakana S, Shiroishi T, Taya C, Yonekawa H.
A small deletion hotspot in the type II keratin gene mK6irs1/Krt2-6g on mouse chromosome 15, a candidate for causing the wavy hair of the caracul (Ca) mutation.
Genetics. 2003 165:721-733.

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