| Procedure | Acoustic startle and Pre-pulse Inhibition (PPI) v1 | ||
|---|---|---|---|
| Pipeline | IMPC_adult_v2-LaterOnset | Screen Age (week) | 10-50w |
| Parameter | Response amplitude - PP1 | ||
| Strain | Condition 1 | Pipeline(s) | Tested Day (Age) |
|---|---|---|---|
| IMPC_adult_v2-LaterOnset | |||
| C57BL/6NJcl | Late | ♀: 11 ♂: 9 |
2015/10/13 - 2016/07/20 (10.36 - 51.07) |
| Early | ♀: 14 ♂: 13 |
| Factor | df | Bartlett's K2 | p |
|---|---|---|---|
| condition1 | 1 | 2.544973 | 0.1106458 |
| sex | 1 | 3.289592 | 0.06972036 |
| Factor | mean | median | SD | SEM | N |
|---|---|---|---|---|---|
| condition1 - sex | |||||
| Early(10w) - Female | 0.08 | 0.07 | 0.02 | 0 | 14 |
| Early(10w) - Male | 0.07 | 0.07 | 0.02 | 0.01 | 13 |
| Late(50w) - Female | 0.1 | 0.1 | 0.03 | 0.01 | 11 |
| Late(50w) - Male | 0.08 | 0.08 | 0.01 | 0 | 9 |
| Signif. codes ***: <0.001 **: <0.010 *: <0.050 †: <0.100 |
||||||
| Factor | df | Sum Sq. | F value | Pr(>F) | Signif. | |
|---|---|---|---|---|---|---|
| condition1 | 1 | 0.0025457 | 5.3536 | 0.02553 | * | |
| sex | 1 | 0.0003369 | 0.7086 | 0.40458 | ||
| condition1:sex | 1 | 0.0004206 | 0.8845 | 0.35223 | ||
| Residuals | 43 | 0.0204471 | ||||
| Level | Difference | Lower | Upper | Adjusted p |
|---|---|---|---|---|
| Late(50w) - Early(10w) | 0.0151 | 0.00209 | 0.0280 | 0.0239 |
| comment |
|---|
| Response amplitude - PP1 was significantly increased in 50-week-old mice (Late) relative to 10-week-old mice (Early) (p<0.05). |