The grip strength test is used to measure the neuromuscular function as maximal muscle strength of forelimbs and combined forelimbs and hind limbs. These are assessed by the grasping applied by the mouse on a grid that is connected to a sensor. Three trials are carried out in succession measuring forelimb-strength only, followed by three successive trials measuring the combined forelimb/hindlimb grip strength. All grip strength values obtained are normalized against mouse body weight.
Description | MP Term or Comment |
---|---|
abnormal grip strength | MP:0001515 |
Mice with missing digits (e.g. after toe clipping) should be omitted from this test. Behavioural parameters may be influenced by circadian rhythm therefore testing should be routinely carried out around the same time of day to obtain balanced and valid results. Avoid testing immediately after light-dark transition as behavioural outcome may be affected.
Name | Type | Increment | Option | Unit | Data Type | Derived |
---|---|---|---|---|---|---|
Forelimb grip strength measurement | seriesParameter | 1, 2, 3 | g | FLOAT | ||
Forelimb and hindlimb grip strength measurement | seriesParameter | 1, 2, 3 | g | FLOAT | ||
Forelimb grip strength measurement mean | simpleParameter | g | FLOAT | Mean of Increments (Forelimb grip strength measurement) | ||
Forelimb and hindlimb grip strength measurement mean | simpleParameter | g | FLOAT | Mean of Increments (Forelimb and hindlimb grip strength measurement) | ||
Forelimb grip strength measurement max | simpleParameter | g | FLOAT | Max of Increments (Forelimb grip strength measurement) | ||
Forelimb and hindlimb grip strength measurement max | simpleParameter | g | FLOAT | Max of Increments (Forelimb and hindlimb grip strength measurement) | ||
Forelimb grip strength normalised against body weight | simpleParameter | FLOAT | (Forelimb grip strength measurement mean/Body weight) | |||
Forelimb and hindlimb grip strength normalised against body weight | simpleParameter | FLOAT | (Forelimb and hindlimb grip strength measurement mean/Body weight) | |||
Body weight | simpleParameter | g | FLOAT | |||
General comments about the mouse | simpleParameter | TEXT | ||||
Equipment ID | procedureMetadata | TEXT | ||||
Equipment manufacturer | procedureMetadata | Bioseb | TEXT | |||
Grid model | procedureMetadata | HMGU plate | TEXT | |||
Experimenter ID | procedureMetadata | TEXT | ||||
Equipment model | procedureMetadata | Bio-GS3 | TEXT | |||
Date equipment last calibrated | procedureMetadata | DATE |