| Procedure | Hematology Blood collection for hematological test v2 | ||
|---|---|---|---|
| Pipeline | IMPC_adult_v2-LaterOnset | Screen Age (week) | 16-56w |
| Parameter | Red blood cell distribution width (RDW) | ||
| Strain | Condition 1 | Pipeline(s) | Tested Day (Age) |
|---|---|---|---|
| IMPC_adult_v2-LaterOnset | |||
| C57BL/6NJcl | Late | ♀: 10 ♂: 8 |
2015/11/24 - 2016/08/29 (16.36 - 56.64) |
| Early | ♀: 14 ♂: 11 |
| Factor | df | Bartlett's K2 | p |
|---|---|---|---|
| condition1 | 1 | 2.476364 | 0.1155692 |
| sex | 1 | 4.269242 | 0.03880823 |
| Factor | mean | median | SD | SEM | N |
|---|---|---|---|---|---|
| condition1 - sex | |||||
| Early(16w) - Female | 13.01 | 12.95 | 0.38 | 0.1 | 14 |
| Early(16w) - Male | 12.85 | 12.6 | 0.48 | 0.15 | 11 |
| Late(56w) - Female | 12.9 | 12.9 | 0.44 | 0.14 | 10 |
| Late(56w) - Male | 13.64 | 13.65 | 0.56 | 0.2 | 8 |
| Signif. codes ***: <0.001 **: <0.010 *: <0.050 †: <0.100 |
||||||
| Factor | df | Sum Sq. | F value | Pr(>F) | Signif. | |
|---|---|---|---|---|---|---|
| condition1 | 1 | 0.8370 | 4.0286 | 0.051701 | † | |
| sex | 1 | 0.4962 | 2.3879 | 0.130351 | ||
| condition1:sex | 1 | 2.0784 | 10.0032 | 0.003023 | ** | |
| Residuals | 39 | 8.1032 | ||||
| Level | Difference | Lower | Upper | Adjusted p |
|---|---|---|---|---|
| Late(56w):Female - Early(16w):Female | -0.1143 | -0.6207 | 0.392 | 0.92970 |
| Early(16w):Male - Early(16w):Female | -0.1597 | -0.6526 | 0.333 | 0.82034 |
| Late(56w):Male - Early(16w):Female | 0.6232 | 0.0811 | 1.165 | 0.01877 |
| Early(16w):Male - Late(56w):Female | -0.0455 | -0.5799 | 0.489 | 0.99574 |
| Late(56w):Male - Late(56w):Female | 0.7375 | 0.1573 | 1.318 | 0.00795 |
| Late(56w):Male - Early(16w):Male | 0.7830 | 0.2146 | 1.351 | 0.00360 |
| comment |
|---|
| RDW was significantly increased in 56-week-old mice (Late) relative to 16-week-old mice (Early) in only male (p<0.01). |