Procedure Hematology Blood collection for hematological test v2
Pipeline IMPC_adult_v2-LaterOnset Screen Age (week) 16-56w
Parameter Red blood cell count (RBC)
Strain Condition 1 Pipeline(s) Tested Day
(Age)
IMPC_adult_v2-LaterOnset
C57BL/6NJcl Late ♀: 10  ♂: 8 2015/11/24 - 2016/08/29
(16.36 - 56.64)
Early ♀: 14  ♂: 11
Raw Data

Bartlett test result
Factor df Bartlett's K2 p
condition1 1 3.911045 0.04796976
sex 1 0.3813435 0.5368851

Summary statistics
Factor mean median SD SEM N
condition1 - sex
Early(16w) - Female 10.47 10.5 0.41 0.11 14
Early(16w) - Male 11.02 11.06 0.38 0.12 11
Late(56w) - Female 10.01 10.07 0.27 0.09 10
Late(56w) - Male 10.32 10.34 0.26 0.09 8

ANOVA result
Signif. codes ***: <0.001
**: <0.010
*: <0.050
†: <0.100
Factor df Sum Sq. F value Pr(>F) Signif.
condition1 1 3.3703 27.5104 5.765e-06 ***
sex 1 2.1191 17.2978 0.0001697 ***
condition1:sex 1 0.1576 1.2866 0.2636049
Residuals 39 4.7778

Tukey multiple comparisons of means
Factor: condition1
Level Difference Lower Upper Adjusted p
Late(56w) - Early(16w) -0.566 -0.784 -0.347 6.11e-06

Factor: sex
Level Difference Lower Upper Adjusted p
Male - Female 0.447 0.230 0.664 0.000170



FM_02_U_barchart.png

comment
RBC was significantly decreased in 56-week-old mice (Late) relative to 16-week-old mice (Early) (p<0.01).