| Procedure | Immunophenotyping test v.1.0 | ||
|---|---|---|---|
| Pipeline | IMPC_adult_v2-LaterOnset | Screen Age (week) | 16-56w |
| Parameter Group | T cell (panel A) | ||
| Parameter | CD4 Central Memory T | ||
| Strain | Condition 1 | Pipeline(s) | Tested Day (Age) |
|---|---|---|---|
| IMPC_adult_v2-LaterOnset | |||
| C57BL/6NJcl | Late | ♀: 3 ♂: 3 |
2015/11/26 - 2016/08/30 (17.07 - 56.93) |
| Early | ♀: 3 ♂: 3 |
| Factor | df | Bartlett's K2 | p |
|---|---|---|---|
| condition1 | 1 | 3.803071 | 0.05115867 |
| sex | 1 | 0.4755317 | 0.4904533 |
| Factor | mean | median | SD | SEM | N |
|---|---|---|---|---|---|
| condition1 - sex | |||||
| Early(16w) - Female | 59.67 | 59.01 | 2.42 | 1.4 | 3 |
| Early(16w) - Male | 63.7 | 63.86 | 1.86 | 1.07 | 3 |
| Late(56w) - Female | 31.64 | 34.67 | 5.57 | 3.22 | 3 |
| Late(56w) - Male | 43.48 | 41.66 | 4.01 | 2.31 | 3 |
| Signif. codes ***: <0.001 **: <0.010 *: <0.050 †: <0.100 |
||||||
| Factor | df | Sum Sq. | F value | Pr(>F) | Signif. | |
|---|---|---|---|---|---|---|
| condition1 | 1 | 1745.81 | 123.8019 | 3.805e-06 | *** | |
| sex | 1 | 188.97 | 13.4007 | 0.006395 | ** | |
| condition1:sex | 1 | 45.79 | 3.2469 | 0.109234 | ||
| Residuals | 8 | 112.81 | ||||
| Level | Difference | Lower | Upper | Adjusted p |
|---|---|---|---|---|
| Late(56w) - Early(16w) | -24.1 | -29.1 | -19.1 | 3.81e-06 |
| Level | Difference | Lower | Upper | Adjusted p |
|---|---|---|---|---|
| Male - Female | 7.94 | 2.94 | 12.9 | 0.0064 |
| comment |
|---|
| CD4 CM T was significantly decreased in 56-week-old mice (Late) relative to 16-week-old mice (Early) (p<0.001). |